Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09850 Olaparib GSE70138 HA1E Human 24h 10uM EID0076
Types Number Response transcription factors
Up-regulation 688 CEBPD; KLF3; TAF5; SOX2; PRRX1; SSBP2; ZNF586; KAT6A; SSBP3; ZNF350; ZNF665; ZBTB39; ZNF93; INSM1; TFAP2A; BCL11A; ZNF91; RFX2; GLI2; IRF1; ATF7; ZSCAN18; ZNF117; BRWD1; JUN; LMX1B; ZNF264; ZNF671; TAF1C; KLF9; HOXA4; EPAS1; NHLH1; TONSL; ARID3B; KDM5B; ID4; TAF6L; TBX6; ZNF135; ZBTB44; RAD21; POU6F1; TAF1; ZNF415; PRDM1; ACTL6B; ZNF235; RFX1; SP1; FOXP3; PEG3; ZNF221; ZNF331; CIITA; ZNF814; CNOT3; ZNF180; CD3D; RARG; TCEA2; JAK2; HIF3A; ZBTB7B; ZNF701; FOXH1; EZH1; MDM2; ZNF154; HOXB3; ELK4; ZKSCAN8; HNF4G; CEBPE; ZNF286A; ZNF155; NR0B2; ZNF253; MED12; HHEX; ZNF225; THRA; ZNF711; NCOA3; EMX1; CALCOCO1; SIX5; FOXF1; ZNF770; AFF3; NKX2-5; TFDP3; MYNN; CUX2; ZNF79; ZNF211; ETV3; RBL2; ZNF177; MED31; ZMYND11; TGFB1; ZNF175; ZSCAN31; ZNF134; ZFPM2; MZF1; TBX10; TFAP4; NR6A1; RFXAP; CHD2; GTF2I; EYA3; WHSC1L1; NPAS1; ZNF695; NKX6-1; ZNF667; NEUROD4; MEF2C; ZSCAN2; ZXDB; CTCF; ESRRG; POU2F2; HOXC8; DCC; RBPJL; IKZF4; BARX2; LHX2; RAX; ZNF132; ZNF768; ASH1L; CBFA2T3; SIX6; STAT4; FLI1; ONECUT1; ZNF778; SOX3; ZNF394; TAF4; ZNF83; FOXF2; ZNF787; ZFP64; GFI1; NR2F6; ZFP2; PHIP; ZNF273; AFF2; ZNF43; ZNF816; TCF21; CLOCK; THRB; GRIP1; NEUROD6; ZNF33B; ZBTB3; BARX1; ZNF205; SUPT7L; ZNF500; SCAI; HOXA2; SOHLH2; MECP2; NR1I2; E4F1; MYCL; IKZF2; CARF; ZBED1; LMO1; NCOR1; GTF2A1; THAP11; ZNF639; TLX1; ZNF614; JUP; EHF; FOXL1; ZNF85; ZNF74; HOXA3; CRX; HEYL; MDM4; SNAPC4; VSX1; YBX2; NR4A2; HOXC13; TBX5; SKIL; FEV; WWP1; SOX18; NR2F1; ZNF174; DLX6; ZNF606; HES2; CIR1; MEIS2; PRDM13; ZNF549; RUNX3; TULP1; EHMT1; HOXA6; ZNF276; REL; FEZF2; TUB; NFIX; ZNF136; CBX2; CAMTA2; TAF5L; LHX3; TBX21; TBX4; AEBP1; PHF8; CAMTA1; CBFA2T2; ZNF112; NFKB2; LIN28A; NEUROD1; EVX1; ETS2; ZNF611; POU3F2; DBP; STAT2; RFX3; NEUROG3; ZNF329; ZIM2; MBD1; SP4; HIPK2; MYF5; TBX1; ZNF287; KLF13; EHMT2; FOXJ2; MAML3; ZNF749; ALX3; SP2; ZBTB16; MYCN; PAX7; PRDM9; DLX2; FOS; ZNF124; ZNF557; SOX17; LHX1; NEUROD2; HR; POU6F2; ATF6B; PAX6; L3MBTL1; ZFHX2; KDM5C; DNMT1; TSHZ2; TCF7L2; TLX2; PNRC1; ZBTB6; ZNF460; HLX; MNDA; TEF; PAX1; ZNF484; ZKSCAN3; BNC1; ZNF506; TRPS1; ZIC3; NFE2L2; CRTC1; PKNOX2; PRDM14; TULP3; SATB1; ALX4; TBR1; HDAC9; ZNF675; ZHX2; ZNF613; ETV7; ZXDC; POU2AF1; ZNF337; NAB2; ZNF354A; ZNF250; ZNF544; HOXB2; NFKBIB; ZNF345; ZNF780B; SOX21; SOX14; ID1; ZNF34; KMT2B; ZNF467; ZNF41; MLLT1; RORC; HIC1; HNF4A; ATF6; ARID1A; PIAS4; ZNF556; PRDM2; ZKSCAN1; ASCL3; TLX3; ZNF669; GBX2; ARID3A; NKX3-2; ZNF343; NEUROG1; OVOL2; MED25; PITX3; ZNF208; PRDM8; KAT6B; PPRC1; PCGF3; NSD1; GATA4; HDAC11; SIX3; FOXB1; NANOG; PBX1; ZNF223; TRAF6; WNT4; NKX2-2; ELF3; GATA6; IRX4; ZNF254; PAWR; NFYA; MED20; ZNF232; NFE2; PRDM10; ZNF84; SRF; TP73; NR2C2; FOXA2; ZFP37; TP63; ZBTB7C; ZSCAN9; PROP1; NHLH2; ARL2BP; ZFP69B; ZNF623; HOXB5; PRDM5; TBL1Y; POU3F4; CNOT6; AIRE; TULP2; ZNF710; SALL2; ZBTB43; ZNF248; CREB1; ZIC1; IRF8; SSX3; VHL; ZNF444; ZNF419; KLF1; SOX11; TAF4B; PGR; PPARA; VAX2; TRIM24; POU2F3; ZNF407; AFF4; ZNF224; IRF9; HMX1; ZNF157; POU2F1; PAX3; ONECUT2; ZNF222; ST18; GSC2; MXD1; ZNF257; ZNF835; HES1; GATA1; KLF11; PEX14; MAP3K10; ZNF44; ZNF507; ARRB1; ZNF688; CDK9; TFEB; GLI1; ZNF8; ZNF696; ZFY; NEUROG2; PPARGC1A; PBX2; TTF2; BRDT; ZNF571; RNF2; SOX15; ZNF471; SSX7; SRY; ZNF682; ATN1; WT1; ZNF10; TAL1; TCF3; UBE3A; HOXB8; GFI1B; ZNF573; FOXN3; CERS4; ZNF81; HOXB1; ZNF227; YEATS4; VENTX; NCOA2; ZNF215; ZNF550; MAPK8IP1; ZKSCAN4; POU1F1; NFATC3; ZNF304; CEBPG; KLF4; BNC2; CBX7; PAXBP1; HSF4; MYT1; PAX4; ZNF45; MTA1; GBX1; ZNF214; CDIP1; FOXJ1; ZNF580; ZNF80; NACA2; KAT2A; SHOX2; SOX12; RSF1; ZFX; ZNF334; GMNN; ZNF480; RYBP; SETDB1; PLAG1; NFYB; ZNF562; ZNF442; TAF9B; AR; ZNF324; HOXD12; BAZ2A; HIPK3; CHD9; ORC2; MYEF2; ZBTB20; POU5F1B; YAP1; MYBL1; SNAI1; ZNF107; LZTR1; EN1; POU4F2; KDM5D; HMBOX1; NR4A3; ZNF391; SMARCD1; FOXI1; LYL1; SUV39H2; BTAF1; GCM2; IKZF5; ZNF75D; PPP1R13L; JUNB; RCOR3; HOXC4; ERBB4; CNOT2; ZNF440; KLF15; FOXE1; ZNF236; RXRA; MBD4; OLIG2; TOX3; MYF6; ASCL1; CITED2; FOXL2; ATOH1; RING1; SMAD4; ZNF141; MED13; ZNF652; ZNF492; IRF6; BPTF; HEY2; HOXB13; NFATC4; IL16; BRIP1; HSF1; SPI1; MLLT10; ISL1; ZNF493; CAPN15; MYRF; SCRT1; NR1I3; HBP1; VGLL1; ZNF268; ZEB1; ZFHX3; RCOR1; STAT3; EMX2; SMAD5; SNAI2; NR0B1; FOXK2; PROX1; UTF1; MGA; ZNF551; CREM; RBFOX2; ZNF195; E2F8; ID3; KLF10; HLF; NR2E1; MEIS1; TRIP11; SOX13; ZNF552; TRRAP; NR5A2; EGR4; HOXD11; CITED1; CHD7; HIC2; TLE2; ZNF239; JUND; PIAS1; TCF4; SPIB; HOXD3; MLXIP; NR1D2; BHLHE41; MAK; SUPT3H; KLF7; HIVEP1; ZNF423; ZMYND8; ZNF426; KLF6; INSR; ZNF160; SKI; HMGB2; BACH2; DLX5; ADNP; SALL1; TFEC; SF1; MED21; ELF4; TERF1; MXI1; ZNF512B; SPEN; SMARCC2; ZNF430; SPDEF; NR1H2; ASH2L; TFCP2; SERTAD2; RNF141; GRHL2; MEOX1; TRIM22; LITAF; HIRA; HMGB3; CALR; SMAD7; YBX3; ARNT2; HEY1; ZNF217; NKX2-1; PAX5; ZNF274; TOX; MKL2; HOXD1; STAT1; ESR1; MAF; MYB; ARID5B; FOXG1; IFI16; ZBED2; HOXB6; EGR2; PBX3; DACH1
Down-regulation 168 CRK; PUF60; DRAP1; ATF4; FHL2; XBP1; PCBD1; HMG20B; ELF1; TCF12; MAGED1; NFIL3; RNF4; SMARCA4; SUV39H1; HOXA10; NONO; PSMD9; EZH2; PQBP1; PAX8; YBX1; GABPB1; RBBP7; ZMYM2; MED6; NR2F2; GTF2A2; MYBL2; SOX4; TAF1D; CBX3; PSPC1; TRIM32; SMAD2; BCL10; ZNF226; SCAND1; BIRC2; FOSL1; USP22; ECD; KDM2A; TBP; UBE2I; RNF10; AATF; FOXJ3; NKX3-1; CCNA2; ELK3; HMGN3; WWC1; RBBP4; PHF20; SP110; STAT6; GTF3A; HOXC6; SMARCC1; KDM4A; MYCBP; CBFB; SNW1; AFF1; AIP; TRIM28; DPF2; SND1; ZNF593; CRY1; ZNF410; ARNTL; SETD2; TTF1; SP100; ZMIZ2; PMF1; VGLL4; LEF1; SUB1; NEDD8; ZZZ3; FOSL2; SREBF1; ITGB3BP; SOX10; DEK; PIAS2; TSC22D3; ZEB2; XRCC6; FOXC1; SMARCE1; NCOR2; LMCD1; MED23; NPM1; TRIM16; KLF2; DAXX; NUP62; NFKBIA; CTR9; MITF; CEBPB; POLR2A; BTF3; CCNC; TSC22D1; ARID4B; HSBP1; SFPQ; DNMT3B; TFAM; EDF1; ZBTB18; BATF3; HTATIP2; TBPL1; TGFB1I1; JARID2; SAP18; MBD2; PDLIM1; PCGF2; ELF5; RNF6; BCL6; ZNF189; HLTF; ING2; NRBF2; HDAC1; BASP1; MSX1; RBBP8; BRD2; PTTG1; PRKDC; RBM14; PLAGL1; TAF10; SMAD3; EGR3; FLNA; UBP1; ID2; ENO1; PEX2; TBL1XR1; TBX3; BHLHE40; SIX1; BRD8; EYA1; AHR; BAZ1A; TRIP6; TLE1; PSIP1; MED1; TSC22D2; ZFP36L1; TBL1X; TP53; WWTR1; RELB