Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09809 Geldanamycin GSE70138 HA1E Human 24h 3.33uM EID0003
Types Number Response transcription factors
Up-regulation 86 CEBPD; FOXO4; CBX5; MZF1; CITED2; KDM5C; BRD8; CNOT2; INSR; CALCOCO1; KAT6A; BAZ2B; RAD21; LDB1; PHIP; ZBTB44; PFDN5; E2F8; ARID4B; ZKSCAN4; ZNF175; SMARCD1; FOXK2; PAX6; PHF1; ZNF544; ZNF45; ATF7IP; PNRC1; ZNF345; HBP1; CBFA2T3; CREG1; JUP; TFDP2; HDAC5; ARID4A; ZNF665; ZNF263; ZNF117; FOS; TULP4; PIAS1; SALL2; TXNIP; TCF7L2; ZNF124; ZNF304; ZNF587; MED23; NEUROD1; SMARCD3; DLX4; HDGF; ZNF432; AFF1; ATF5; MKL2; INSM1; HMGN3; TOB1; ZNF415; TRIM28; HMGB2; PBX1; NFAT5; PRDM2; SAP18; SSBP3; HOXD1; TP63; NCOA3; MNDA; RSF1; LITAF; PAX5; BCL11A; NKX2-1; MXI1; ASCL1; ZNF331; EMX2; ST18; ERBB4; TOX; PSIP1
Down-regulation 71 FOSL1; NFKBIA; MYC; DRAP1; BHLHE40; EGR1; ELK3; RELB; SOX4; BIRC2; FOXO3; WDR77; ETS1; KLF6; JUN; HIF1A; RUNX1; ID3; YAP1; PREB; HMGA2; NFKB1; LMCD1; SOX9; KLF10; SCAND1; DLX2; HIVEP2; NKX3-1; ZMIZ1; PTRF; LEF1; TLE1; FOXD1; TRIM16; SMAD2; CBFB; NCOR2; BHLHE41; SERTAD2; C1QBP; SNAI2; CREB3L1; KLF2; KLF4; FOSB; SATB2; HOXB6; JARID2; SIX1; ID4; ETV4; LIN28A; EGR3; ETS2; EGR2; HMGA1; SMAD7; FLNA; ID1; HES1; ATF3; TFAP2C; PBX3; KDM5D; DACH1; SATB1; PPARG; MEIS1; ADRB2; TBX2