Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09808 Geldanamycin GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 145 CEBPD; FOXO4; ZNF446; PNRC1; ARID4B; TULP4; CBX5; SIRT2; SUPT5H; ZNF813; ARID4A; ZNF345; ZFP64; SIX6; OLIG2; NCOA2; ZNF571; CDK7; ZNF223; ZNF544; ELF1; PBX1; DMRT1; KMT2B; RAD21; ZNF587; JUP; HMGB2; ZNF264; ZNF473; ADNP; HNF4G; HBP1; CALCOCO1; ZNF394; ZNF606; PHF8; TRIM28; SIM1; CREG1; COPS2; ZNF33B; NR3C1; ASXL1; NKX2-1; ZNF175; ZNF302; TTF1; TCF4; TFCP2L1; MED23; ZSCAN31; ZNF45; ZNF816; RFX7; BRD8; ARID5A; MAGED1; ZNF184; ZNF574; INSM1; ZNF536; THAP10; TMF1; NCOA6; NFAT5; RELA; TP63; TDP2; BACH2; SKI; FOXA1; ZNF415; SMARCA2; ASCL1; ZNF304; SALL1; BCLAF1; FLI1; YBX3; ZNF432; TFAP2A; E2F8; TGIF1; HDGF; ZNF117; PIAS1; ZNF329; TXNIP; ZNF331; TFAM; IRX5; NLK; ARID5B; PPARG; ZSCAN18; EYA1; TRIP6; CREBL2; NR3C2; ZNF165; TLE4; SIAH2; FOXO1; ING3; AFF1; RSF1; KLF9; TOB1; RORA; HOXD1; POU4F1; CRYM; RBPMS; RLF; FOXF1; INSR; ZEB2; IRF6; MAF; PDLIM1; HOXB13; ZBTB38; MYB; TBX3; EHF; ST18; ID4; LITAF; IRF8; FOXF2; NR1D2; KDM5D; KLF5; IRF4; ZEB1; HEY1; STAT4; MEOX2; NR1H2; SATB1; GATA3; TRIM29; PSIP1; TOX3
Down-regulation 72 LOXL2; FOSL1; SOX4; DRAP1; NFKBIA; MYC; ETS1; ZNF593; RELB; HIF1A; BHLHE40; MTA1; WDR77; EGR1; BIRC2; JUN; SCAND1; ZNF32; KLF7; NFIC; PSMC3IP; PQBP1; YAP1; PSMC3; ELK3; ENY2; WT1; SNAI2; CUX1; EDF1; APEX1; SREBF1; ZFP36L1; FOSL2; KLF10; PTRF; RFXANK; SERTAD2; GATA6; ZMIZ1; HSBP1; TEAD4; SMARCE1; NCOR2; KLF6; TLE1; CARHSP1; LIN28A; DLX2; GTF3A; PRRX1; HOXA10; TGFB1; PLAGL1; FLNA; KLF2; GATAD2A; NR2F2; COPS5; RBBP8; IRF9; VDR; NFE2; JUNB; MAFB; MEIS1; HES1; NFE2L3; PBX3; ID1; TBX2; GATA2