Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09800 Withaferin-a GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 46 KDM5A; SOX10; BRD8; ZNF500; PIAS4; SSBP2; PEX14; JUND; ZBTB16; ZNF573; PCGF2; HBP1; UBE2B; MLXIP; KLF6; TBL1XR1; IFI16; YWHAB; SPIB; CTNNB1; ST18; LMCD1; CBX7; ZMYND8; TCF4; TGIF1; HTATIP2; ZEB2; MEOX2; CD3D; MNDA; TCF7; ZNF536; ARNT2; PPARG; RBPMS; BCL11A; ZHX2; MXI1; HOXB7; POU2AF1; HOXC6; IRF8; PEG3; SOX11; ABL1
Down-regulation 32 HOXA5; RFX5; CREB1; ZBTB38; MED24; SOX9; NFATC1; CBX3; ISL1; DACH1; ZEB1; HDAC9; NR2F1; MEIS1; ELK3; TAF1D; RYBP; PBX3; ERG; HMGN3; MSX1; ID3; MYCN; MAFB; ASCL1; EYA2; SATB1; HEY1; SNAI2; ID1; GATA2; TBX2