Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09798 Withaferin-a GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 104 FOXD1; PHIP; FOXO4; RNF111; HTATIP2; MAFG; SAP130; TRIP11; NFYC; NFE2L1; ZNF8; ZNF267; ZNF544; TCF7L2; BATF; BRF2; CAMTA2; AATF; ETV5; ZNF217; TULP4; CDC5L; NCOA2; TCF20; ARID4B; TAF5; SNIP1; HLX; HDAC1; YAP1; NCOA6; PRDM10; ZNF394; TAF1A; ZNF227; HMGA2; POLR3C; CHD1; PIAS1; TSG101; MED13; KMT2A; ZNF14; CREG1; SERTAD2; E2F6; SUPT4H1; TXNIP; ZNF175; EP300; PSMC3; MED24; TGFB1; RREB1; RUNX3; NR0B1; TDP2; SP2; HEY2; ATF5; CHD8; ATF7IP; SFPQ; ADRB2; SP3; PIR; THAP10; ZNF148; MED23; HOXA1; NR1H4; INSR; ZNF430; SSBP3; ZBTB20; IRF6; AGO2; HOXD1; EYA1; CEBPZ; ZNF226; BRD4; ERBB4; HIC2; NKX3-1; HEY1; CREB3L2; SATB2; BATF3; ARNT2; NCOA3; ZHX2; MYRF; TFDP2; HMGN3; MKL2; BTG1; HOXB7; ZBTB16; MXI1; SNAI2; OSR2; GATA2; SATB1
Down-regulation 77 NFKBIA; HMG20B; LOXL2; BASP1; MYBL2; XBP1; MYC; HDAC6; JUND; SOX4; RELB; CHD3; BHLHE40; NONO; HOXA5; ZNF22; NELFB; MBD4; ZNF672; EDF1; SLC2A4RG; TP53; FOXF1; CRY1; ZNF83; NR4A3; TLE2; ZNF133; SMAD7; NFKB1; CALR; TDRD3; DNMT3B; BRD3; DDX17; NR2F1; LMCD1; PBX1; AES; TCF7L1; TCF4; FUBP1; KLF6; ID4; SIAH2; NKX2-2; NFIB; PTTG1; CARHSP1; ZMIZ1; SMARCD3; TBL1X; ZFP36L1; EHF; TCF21; ZSCAN18; SOX11; ID3; MEIS1; ETS2; E2F5; SMARCA1; ATF3; SHOX2; FOSB; POU2AF1; RBBP8; EGR3; DACH1; ZFPM2; HES1; ABL1; EYA2; MECOM; PBX3; TOX; TBX2