Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09796 Withaferin-a GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 712 CEBPD; SPDEF; SCAI; MEF2C; ZNF154; ZNF273; BRCA1; ZNF235; PRDM14; ZNF274; SIX6; ZNF415; ZNF117; ZNF573; ZNF500; ZNF544; TRIB3; TP73; CBFA2T3; ZNF141; ZNF778; ZNF586; CBX4; CHD2; ZNF85; THRB; SP4; SRY; ZNF8; ZNF75D; VPS72; TBL1Y; ZNF688; FEZF2; ZNF345; PRDM1; ZNF665; ZNF550; LZTS1; ZNF43; ZKSCAN8; RFX3; ZXDC; TULP2; ZNF221; ZSCAN9; ZNF682; GFI1B; ZNF10; RFX1; PROP1; ZBTB3; GBX1; MZF1; SOX3; MAML3; ZNF254; TAF1C; TCEA2; ZNF669; ZNF701; LHX3; ZNF695; HESX1; TBX4; RORB; ZNF814; CARF; ZBTB44; SCRT1; ZXDB; ZNF770; FOXH1; POU6F2; ZNF287; ASH1L; HSF4; SOX21; ZNF180; HIF3A; ZNF391; CDX1; ETV1; HIPK2; ZNF174; ZNF606; ZNF253; ZSCAN32; ASCL3; ONECUT1; POU4F3; ZNF214; ZNF132; ZNF225; NFE2L2; DOT1L; ZNF91; ZNF480; ZNF549; ZFP2; ZNF264; SSBP3; NR5A1; CUX2; NEUROD6; TAF4B; DLX5; ZNF675; NR2E1; ZNF471; ZNF529; NKX3-2; SOX18; NR6A1; NEUROD4; FOXJ2; ZNF780B; PNRC1; PRDM9; CCNH; ZNF136; ZKSCAN3; ZNF83; ZNF394; BRDT; AIRE; TEF; ZNF407; ZNF611; ZNF557; GATA1; PRDM12; TFAP2A; CBX2; PAX6; ZNF223; ZNF667; ZNF155; ZNF343; RORC; VENTX; PAX4; ALX4; IKZF2; HOXB1; TLX3; CDIP1; PIAS4; ZIC3; MAK; ZNF350; NEUROG3; SNAPC4; TAF7L; THAP9; E2F4; ZNF749; HIC2; PAX1; ZNF816; ZNF81; E4F1; ZNF671; SOX13; EMX1; ZNF195; ZNF835; ZNF44; TRIM24; HOXC5; ZNF442; MECP2; ZNF232; CIITA; ETV3; ZNF93; HDAC11; TLX2; ACTL6B; FOXF2; KLF13; BCL11A; FOXJ1; PRDM10; ARID3B; TFDP3; FOXE3; ZNF257; PRDM2; YEATS4; ZNF440; ZKSCAN4; CDX4; ZNF304; LIN28A; ALX3; ZNF484; ZFP69B; GCM1; MED25; ZNF562; POU1F1; ZNF334; ZNF711; FOXN1; GRIP1; MED12; PPARA; ATF7; ZNF239; NOCT; AFF3; ZNF222; ZNF208; ZNF674; GCM2; EN1; FOXP3; TCF21; HOXB8; NEUROG2; NHLH1; MED31; NFATC4; ZNF74; SIX3; HOXA2; FOXL1; SOX14; SOX17; CAMTA2; ZNF362; TBR1; GSC2; PKNOX2; MLLT1; AEBP1; ZNF571; HEYL; ZNF80; ZNF551; ZNF507; ETV2; PDX1; CBX8; HOXA6; SSX7; ING4; ZNF211; FOXD3; HOXD12; IKZF3; SOHLH2; TULP1; POU2F3; PCGF1; KLF8; L3MBTL1; HES2; PAX7; ZNF324; TSHZ2; TUB; ATF6B; FOXB1; ZNF79; VHL; MEIS2; NR1H4; POU3F3; RBPJL; IRF6; MYEF2; POU2F1; AR; ARL2BP; TAF5; ZNF423; TONSL; TBX5; PAX3; HDAC9; MAPK8IP1; PRRX1; HNF4G; MDM4; HMX1; ZNF124; DMRT1; YBX2; UTF1; TBX19; LYL1; ZNF134; SALL2; ZNF135; ATOH1; PRDM13; NFIX; VGLL1; ZNF268; NEUROD2; EP300; ZNF215; CBFA2T2; ZNF331; ZNF142; ZNF157; INSR; DDIT3; ZNF41; OVOL2; BARX1; ZSCAN2; OVOL1; CEBPG; ZNF460; LBX1; KLF15; ZNF177; SOX5; ZBED2; MDM2; RFX2; HINFP; LDB1; ZNF234; NR2C2; ZNF613; ZIC4; LHX2; AFF2; NHLH2; POU6F1; JUP; ZNF202; MAP3K10; RFXAP; ZNF354A; NFKBIB; BRWD1; NEUROD1; SPI1; PRDM5; ZNF112; ZNF224; ZNF623; RING1; KDM5C; KLF3; ASCL2; ZNF492; ERBB4; NRL; EYA3; ESRRB; GTF2A1; LMX1B; TBX1; ZIM2; VSX1; TCF7L2; NKX2-5; ZNF771; ZNF286A; NR1I3; CNOT3; SOX1; GBX2; TAF5L; ZNF493; IKZF4; ZFY; REL; ZNF654; HDAC5; ZBTB7C; RARG; TFAP4; PITX3; SUPT3H; TAF1A; RNF2; E2F1; KDM4C; GON4L; IRF1; SUV39H2; ZBTB6; ONECUT2; SUPT7L; ZNF419; ZBTB43; ZNF324B; SOX15; ZKSCAN5; EZH1; BANP; WNT4; ZNF467; BRD4; ZNF329; ZNF510; ZNF34; SETDB1; ESRRG; MSX2; TLX1; TRIP11; NANOG; TAF6L; TAF1; CBL; DCC; HNF1A; PIAS1; ARNT2; SOX30; CRX; FHL5; ARID3A; SHOX; ZNF227; BNC1; CRTC1; RAX; HNF4A; SIN3B; ZFHX2; NPAS1; SALL1; HIC1; KLF7; HNF1B; ZNF107; THAP10; ZBTB17; FOS; HOXD1; ZNF432; ZNF764; NR5A2; THRA; HLX; PRDM16; MYF5; HBP1; CNOT2; HOXA3; HSF1; ZNF614; SMAD9; SMARCB1; FOXC2; NRF1; MNDA; TBX21; RORA; CSDC2; TAL1; POU3F4; ZFP37; DLX6; POU4F2; ZNF426; ZBTB7B; IRF9; MYT1L; ZSCAN18; OLIG2; FOXD2; JAK2; ZNF33B; ZNF710; THAP7; TULP3; WHSC1L1; IRF3; ZNF335; RXRG; NFE2; ZFPM2; ELK4; TDRD3; STAT4; ZNF506; NR0B1; IRX4; WIZ; USP21; NACA2; TBX6; NFKB2; ZNF23; IFI16; FOXG1; ZFP30; TDP2; ZNF250; FOXN2; HOXC8; CBX7; KLF11; TAF9B; VAX2; NR1H2; POLR3C; ZNF175; FLI1; MXD1; CAMTA1; HIRA; NKX6-1; HOXD3; ZNF528; HIVEP3; HAND2; CEBPA; ZBTB48; FOXE1; PEG3; CIR1; ATN1; ZNF236; HOXD13; ZNF219; EPAS1; FOXM1; FOXF1; ZNF692; LZTR1; TEAD4; NCOA3; ETV7; ZNF589; MYCL; HLF; HMBOX1; KLF4; HAND1; POU3F2; PHIP; DBP; NR2F1; ZNF430; SKIL; NR2F6; SNAI1; PBX1; TERF2; ZNF532; HOXD11; GFI1; CD3D; ZNF813; ZNF133; CREM; SUPT4H1; JUNB; ZNF580; CCNE1; ST18; NCOA2; HOXC11; GRHL2; EHMT2; TRPS1; TP63; MXD3; ID3; ZNF35; FOXI1; SKI; FOXA2; LMO1; MYNN; NR2C1; ZNF205; STAT2; PEX14; BAZ2A; NEUROG1; TCF4; NFIC; ZFHX3; ZNF444; ZHX2; NR4A1; NR4A2; NR0B2; KLF1; CEBPE; ZNF165; MED17; ETV6; HEY2; ZBTB20; ARNTL; ZNF3; WT1; PCGF3; JUN; PLAG1; HHEX; CERS4; ZNF131; ZKSCAN7; ZSCAN31; KAT2B; MYF6; KMT2B; INSM1; PROX1; PHOX2B; CCNT1; E2F5; MYT1; BHLHE41; PITX1; MBD4; BACH2; ESR1; ID4; ZNF14; DLX4; HMGA1; ID1; SP140L; BARX2; TRIM22; ZMYND8; EYA1; IRF2; CEBPB; SHOX2; CREBL2; CRYM; E2F8; ZNF184; RCOR3; TCF7L1; ZFP36L2; FOXA1; HEY1; RSF1; POU5F1B; CDX2; EGR4; ZSCAN16; POU2AF1; ISL1; ZNF652; NPAS2; RBFOX2; SOX11; KDM5D; NLK; SPIB; SNAI2; MXI1; ZNF140; RFXANK; NR3C2; CREB5; NR4A3; LHX6; BNC2; TOX; ZNF536; CITED1; SOX2; IL16; GLI2; MYCN; HDAC4; ZIC1; TERF1; PBX2; CDK9; NKX2-2; ARID1A; YBX3; TBX3; ATF3; TCEA1; HOXB13; TWIST1; TGFB1; ZEB1; GATA6; FOXL2; CREB1; TLE2; TFDP2; ASCL1; MYRF; IKZF1; OSR2; PLAGL1; ZNF160; IRF8; SSBP2; CITED2; ELF3; KLF5; FOSB; MECOM; HES1; E2F2; TFAP2C; PBX3; DACH1
Down-regulation 155 ATF1; BASP1; RHOA; EZH2; PARP1; FHL2; XBP1; NFIL3; HOXA5; NCOA4; SMARCC1; SOX4; RB1; RBBP4; MYC; CCNA2; LOXL2; FOXO3; VEZF1; NEDD8; MYCBP; HNRNPD; NFKBIA; BHLHE40; NUP62; HOXC6; PBRM1; SUV39H1; ENO1; CTR9; HDAC2; RFX5; CNOT1; FLNA; SND1; NR2F2; SNW1; SMAD2; MAGED1; ELF1; MED1; CRK; SFPQ; ECD; CRY1; BMI1; RBM14; SMARCA5; EDF1; NCOR2; AFF1; CBFB; BRD8; STAT6; HDAC1; DEK; SSRP1; EED; TSC22D2; KDM2A; GTF2A2; USP22; SETD2; MTDH; DDX54; FOXJ3; TCF12; NRIP1; ELK3; REST; NPAT; BIRC2; REPIN1; BCLAF1; TEAD1; UBP1; PCGF2; DNAJC1; ZBTB18; PRKDC; PAX8; BAZ1A; HOXA10; RBBP7; ZBTB1; ELK1; TBL1XR1; SMARCA2; NFE2L1; ZNF146; PTRF; HIPK3; RUNX1; SIAH2; SMARCE1; ITGB3BP; NFKB1; CHD7; TADA3; ZBTB38; BRD3; HSBP1; TRIM32; HOXB7; HTATIP2; CCNC; UBE2I; YBX1; TLE1; MED4; FOSL2; CENPF; SETD3; ATF4; CSDE1; RELA; SCAND1; NAB1; USF2; KLF10; CEBPZ; HOXB6; PATZ1; ZMYM2; FOXC1; SREBF1; MEF2A; TAF10; WWTR1; HLTF; DDX5; TRIM16; NELFB; ZEB2; SPEN; YWHAB; MTF2; CBX3; TFAM; CTNNB1; LMCD1; TRIP6; JARID2; HMGB2; PSIP1; SOX9; HMGB1; STAT3; MITF; HOXC10; RBBP8; BTG1; AHR; LEF1; NR3C1