Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09795 Mitoxantrone GSE70138 HA1E Human 24h 0.04uM EID0003
Types Number Response transcription factors
Up-regulation 107 MNAT1; KDM5A; ATF3; FOXN3; HBP1; NFATC4; TXNIP; PBXIP1; CDIP1; BAZ2A; ZNF79; IRF9; NFE2L1; ZNF557; ING4; TRIM22; ZNF394; CUX2; ZNF222; DDIT3; NR0B2; ARNT2; ZNF268; ZFPM2; CREB3; MDFI; PNRC1; TWIST1; HDAC5; RUNX3; RXRA; MDM2; TOX3; TEAD1; MED15; ETV5; HIC2; HEY2; TP63; KLF11; ZNF112; OLIG2; ZNF34; BARX1; ZNF415; TRIB3; PCGF3; MECOM; ZNF140; NEUROD1; TFEC; TFAP2A; JUNB; ZNF232; ZNF117; ASCL1; IRF6; SIX3; NR1D2; CBX7; SP110; ZNF665; ZNF623; CCNC; PAX5; MYCL; INSR; KAT2B; ZNF43; EN1; PDLIM1; DLX5; TOB1; ETS2; RBL2; LITAF; MKL2; NKX2-2; PBX3; TRIM29; KLF9; ZEB1; SP100; CHD7; ZKSCAN1; PRRX1; PPARG; FOXO1; NFE2; ID4; NR5A2; EPAS1; HOXB2; BTG1; MXI1; IRF8; NFAT5; EYA1; NR4A2; SOX11; HEY1; SNAI2; GATA6; EGR2; TRPS1; PEG3; POU2AF1
Down-regulation 55 MYC; CCNA2; SETD2; ZNF146; SSRP1; TBL1X; PPRC1; NFKB1; SMARCC1; UBE3A; TRIM28; CCNE1; UBP1; RUVBL2; BCLAF1; CENPF; HOXC6; RBM14; ORC2; PIAS2; PTTG1; ELK3; TAF10; HNRNPD; FOXM1; HOXA10; CRY1; NR2F2; TSC22D1; GATAD2A; TBL1XR1; RORA; HMGB3; EDF1; FLI1; CUX1; SIAH2; SP3; CARHSP1; HLTF; WT1; WWTR1; KLF6; NKX3-1; FLNA; MEIS1; BMI1; MAFB; IRX5; ESR1; KDM5D; RBPMS; GATA2; NR3C1; TBX2