Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09794 Mitoxantrone GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 139 ZXDC; HINFP; NFATC4; CDIP1; RING1; SETDB1; TP63; ETV5; VPS72; IKZF1; JUP; DDIT3; SNAI2; ZNF415; ZNF195; TRIM22; POLR3C; TOB1; IRF6; KLF5; MAFG; NFRKB; ARNT2; ZNF202; ING4; IRF5; HBP1; ARNTL; FOXJ1; THRB; NR0B2; PRDM14; HOXD1; TDP2; TRIM29; SERTAD2; TFAP2A; ZNF264; LDB1; RUNX3; ZNF573; THAP7; HIPK2; KLF11; TCF7; ZNF141; MDFI; ZNF44; REL; TFEC; ZNF529; LHX3; SAP18; PSMC3; TCF7L2; OVOL2; HDAC9; ZKSCAN4; ZNF611; MED27; EN1; BRD4; ZNF654; NCOA2; ZNF43; SP2; NR4A3; PEX2; KLF13; ARID5A; ZNF544; CARF; PRDM2; TOX; INSM1; ZNF232; PBX3; THRA; TFCP2L1; PRRX1; BCL6; ZNF331; TTF2; SOX9; ZNF83; SIX3; STAT4; YBX3; CDYL; RUNX1; CREBL2; ZNF91; NFIC; ZNF665; ST18; PFDN5; CREM; EGR4; RORA; CAMTA1; GFI1; PDLIM1; ZBED2; TSC22D3; DLX5; TXNIP; SP110; RYBP; NR1H4; ATF3; TGFB1; CERS4; MXI1; IRF9; AEBP1; TGIF1; RXRA; JUNB; CERS6; KLF9; HES1; ZNF160; EPAS1; EHF; HOXB2; EYA1; TWIST1; FOXF2; LITAF; HIRA; EGR2; CEBPB; MAF; NR4A2; ZNF423; ELF3; PEG3; MYRF; ID1
Down-regulation 104 CCNA2; MYC; NFKBIA; GABPB1; UBP1; PARP1; CENPF; SMARCC1; HMG20B; PCBD1; FOXO3; ZFP64; BRD7; SETD2; BCLAF1; ZBTB1; RHOA; CCDC59; NPM1; RBM14; CARHSP1; ZMIZ2; SOX12; ID2; HOXA10; MAZ; HNRNPD; SIAH2; ESR1; E2F8; DNAJC1; KLF6; TCERG1; TBPL1; CBX3; SUB1; BTAF1; NR2F2; FLNA; HMGB2; PAX8; RBBP5; CBFB; BAZ2B; FOXM1; CUX1; REST; FOXJ3; MTDH; LEF1; CARM1; CENPB; ZNF292; THAP11; RUVBL2; ASCL1; WHSC1; BMI1; TBL1X; SFPQ; ZNF146; TBL1XR1; SMARCA1; ID4; TRIB3; YWHAB; SCAND1; HLTF; CHD7; MED1; DNMT3B; TRIM16; IKBKAP; HOXB7; AFF1; RERE; PURA; SATB2; SMAD7; HOXC6; SOX17; MBD2; BNC2; ARID1A; PRKDC; ZBTB38; FOSB; TLE2; SALL1; SMARCA4; KLF2; PTTG1; ZBTB18; MSX1; WWTR1; MYCN; GLI2; MYBL1; WT1; POU2AF1; ABL1; NR3C1; PPARG; TBX2