Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09793	Mitoxantrone	GSE70138	HA1E	Human	24h	0.37uM	EID0003

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	TRIM22; TP63; MNAT1; FHL2; CEBPD; ZNF195; ZNF79; SP110; IRF9; DDIT3; LDB1; HBP1; TDP2; SETDB1; ZNF211; ZBTB43; CDIP1; ZNF544; SIRT7; ZNF43; ZSCAN32; TCEA2; IRF6; MAFG; STAT1; VDR; FOXJ1; TOB1; ZBTB48; ZNF91; ETV5; ING4; ZNF268; CALCOCO1; ZNF557; SNAI2; KLF11; BCL10; MDM2; PHF8; ZNF3; ZNF14; ZNF273; ZNF44; ATF3; HINFP; FOS; ZNF264; ZNF415; FOXA1; KLF5; SRCAP; ZNF117; TRIM29; STAT2; PCGF3; ZNF222; RXRA; SPDEF; PFDN5; MAF; IRF7; ZNF654; ZNF85; TGIF1; ZNF350; HOXD1; YAP1; HMGXB4; ARNT2; ZNF665; ZNF304; RUNX3; KLF13; ZNF232; ZNF219; ERBB4; AR; NHLH2; TFAP2A; OVOL2; SOX9; ZNF136; TFEC; ZNF266; ST18; TSC22D3; CREBL2; CBX7; NFIB; DLX5; YBX3; TBX1; ZNF140; ZBED1; SERTAD2; ZNF573; SMAD3; BRD8; SP100; THAP10; ZSCAN31; ZNF430; CEBPB; RORA; HLX; BCL6; SALL2; ZBTB16; HEY2; CDK9; ZKSCAN1; IFI16; MKL2; STAT4; STAT3; CTNNB1; ZNF189; REL; HLF; EMX2; NKX2-1; BACH2; TCEB2; IRF1; JUP; CERS4; BAZ1A; BCL11A; BHLHE41; TWIST1; EHF; KLF4; TBX3; EPAS1; TXNIP; ZNF331; KDM5D; PDLIM1; IRF8; TRPS1; ELF5; TOX; HOXB2; DACH1; PEG3
Down-regulation	98	CCNA2; MYC; PARP1; RHOA; PCBD1; HNRNPD; TFDP1; XBP1; SMARCC1; GABPB1; CBX3; MYBL2; ATF6; PAX8; STAT5B; BCLAF1; CENPF; NR2F2; UBP1; CUX1; SETD2; ECD; NFIL3; PIAS2; PITX2; HMGB2; MAZ; TCERG1; BMI1; TRIM28; RBM14; CARM1; PURA; SFPQ; KLF2; FOXD1; PRMT2; ZNF587; ID4; RAN; HOXA10; REST; CARHSP1; GATA6; SIM2; FOXM1; TBL1XR1; CREB3L2; HOXC6; TEAD4; ZMYND11; MEF2A; RBBP4; C1QBP; MTDH; DNAJC1; E2F8; GTF2I; MBD2; FOXF1; HDGF; SUB1; SMARCA1; SLC2A4RG; FOXL2; TRIB3; RBPMS; CREB3L1; TLE2; PTTG1; SMARCA4; THAP11; ENO1; DEK; ZBTB38; TCF12; NR2F1; WT1; KLF6; MSX1; WWTR1; ELK3; SMAD6; MAFB; SOX17; MYBL1; SATB1; LEF1; FLNA; ZEB1; MECOM; PSIP1; MEIS1; NR3C1; TBX2; ABL1; PPARG; GATA2