Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09792 Mitoxantrone GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 293 SUV39H1; CEBPD; FOXO4; HCFC2; ZNF557; ZNF211; RORB; TP63; ZNF274; TRIM22; TCEA2; ZNF324; SNAI2; NHLH2; ZNF23; ZNF195; THAP10; CIITA; ZNF79; BCL6; TRIB3; ETV5; EN1; HLF; OSR2; CALCOCO1; IRF6; ZNF75D; ZNF232; MAF; CDIP1; ZNF136; ZNF273; ZNF45; LDB1; ZNF304; ATF3; CUX2; ZNF180; SMARCD2; ZNF141; ZNF394; EGR1; CEBPB; ZNF227; ZNF10; ZNF202; TAF7L; ZNF225; CBX4; TBX3; ZNF184; ZNF345; RUNX3; ZNF223; ZBTB17; MAML3; DDIT3; ZKSCAN5; HLX; PPP1R13L; KLF4; ZXDB; ZNF14; ZNF222; TCF7L2; MED17; HOXD1; SETDB1; CITED2; ZNF415; IFI16; TAF4B; MYF5; ZNF529; ZNF214; KLF11; CAMTA2; ZKSCAN4; ZNF430; ING4; ZNF665; HIF3A; SOX3; GCM1; ZNF43; ZNF500; RORC; ZNF606; SNIP1; CARF; ZNF112; ZNF254; ZNF432; PEG3; ZNF654; CHD2; ZSCAN5A; ZNF544; ST18; ZNF44; MAK; HOXC13; ZNF334; TOB1; HINFP; AR; ZBTB43; HDAC5; TFEC; ZKSCAN8; TDP2; BRDT; ZNF419; ZNF12; FOXJ2; DMRT1; PHF8; ZBED2; ZNF571; ZNF780B; L3MBTL1; PBX1; IRF1; CBX7; PNRC1; MEF2C; STAT2; TSC22D3; TSHZ2; ZFPM2; PRDM13; ZNF268; ZNF200; PRDM2; TBR1; HBP1; MDM2; ZNF682; ZNF688; GLI3; ZNF81; TFAP2C; ARNT2; ZNF331; ZNF264; TULP2; FEZF2; SCAI; ZNF85; HOXD3; ZKSCAN7; ATF5; CBX6; EGR2; ARNTL; ZNF816; ZNF473; ZNF573; SUPT7L; ZNF74; ZNF266; ZNF350; ZNF3; FOXN3; POU2F3; YAP1; NR1H4; ZNF107; NR1H3; ZSCAN9; TTF1; HOXA1; MED23; ZNF302; ZNF492; SUPT4H1; PRDM1; SAP18; CCNT1; PHIP; TRIM29; VDR; SOX18; SIN3B; SPDEF; ZNF695; TWIST1; KLF5; PRRX1; RXRA; ISL1; ZIM2; HIPK2; ZNF286A; ZNF117; ZNF224; EHF; ZNF257; NEUROD1; ZNF580; TAF1A; NR2C1; ARID5A; ZNF91; IRF9; ZNF467; IRX4; ZNF623; TGIF1; HAND1; FOXF2; BNC1; HHEX; ETS2; SKIL; IRF8; ZNF354A; PAXBP1; CEBPG; STAT4; EPAS1; HDAC4; YBX3; PLAGL1; LHX2; MYCL; ZNF83; ID3; CREG1; PLAG1; TBX1; INSR; BRD2; AHR; RNF141; REL; CREM; FOXO1; ZNF267; BPTF; RORA; NRBF2; RYBP; NR4A3; SP110; FOS; ZNF175; SOX9; KDM5D; EMX2; ZKSCAN1; NFIB; EP300; SP140L; ZNF536; BCL11A; CD3D; ZIC3; NR2F1; NKX2-1; SSX1; BRD4; HDAC9; HEY1; JUP; ZNF423; JUNB; EYA1; NCOA3; MNDA; MXI1; TCF7; CITED1; NR1H2; TSC22D1; MYRF; TRIP6; ZFP36L2; NKX3-1; HIRA; MAFB; MITF; ZBTB16; DACH1; TXNIP; TOX; POU2AF1; BHLHE41; SOX2; HES1; LITAF; ADRB2
Down-regulation 114 PARP1; MYC; CCNA2; XBP1; LOXL2; HNRNPD; NFKBIA; PAX8; SMARCC1; PCBD1; FOXD1; TFDP1; RHOA; SFPQ; ECD; GABPB1; KLF6; TCERG1; CUX1; BRD7; RBM14; CREB3L1; FOXO3; CNOT1; RBBP4; CBFB; PRMT2; TBL1XR1; WHSC1; CHAF1B; STAT5B; CBX5; SF1; CENPF; SSRP1; ZFP64; VEZF1; EDF1; ENO1; REPIN1; ZBTB1; CHD7; HOXA10; CBX3; CHD3; CLOCK; BCLAF1; PRKDC; TGFB1I1; ORC2; ZMIZ2; BAZ1B; DNMT3B; NFKB1; CCNC; FOXC1; DEK; CARM1; USP22; SLC2A4RG; MAGED1; C1QBP; NR2F2; SMARCA4; PURA; KLF2; RELA; NPAT; BRD3; UBE2I; CREB3L2; TCF12; DNAJC1; YWHAB; HMGB1; WWC1; AFF1; RFXANK; NPM1; SMAD2; SMAD1; THAP11; NAB1; IKBKAP; SP3; ARNTL2; PITX2; ID4; MED1; GTF2IRD1; HOXC10; STAT6; HLTF; WT1; ZMIZ1; E2F5; HMGA1; HOXC6; PDLIM1; SUB1; LEF1; SOX17; NRIP1; ZBTB38; RBBP8; ASCL1; SATB2; GLI2; PSIP1; ESR1; ZIC1; SATB1; NR3C1; PPARG