Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09790 Mitoxantrone GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 353 CEBPD; KDM5B; HMGA2; CDX1; ZNF154; MEF2C; JUP; ARL2BP; HIF3A; GFI1B; RING1; CIITA; TRIB3; BCL11A; ZNF274; SPDEF; ZXDC; PRDM14; SRCAP; CDIP1; SIX6; ONECUT1; ZNF467; MAML3; GBX1; ASCL3; SMARCB1; NFKBIB; ETV1; HIPK2; PRDM12; SOX21; FEZF2; SRY; NFATC4; LHX3; VPS72; NR0B2; CBFA2T3; ZKSCAN8; HDAC11; CUX2; MECP2; TCEA2; RFX1; NKX3-2; ZNF688; ZNF235; ZNF415; THRB; BARX1; ZFHX2; ZNF667; RFX3; ATOH1; ZNF835; HLX; NEUROD4; NR5A2; TBX10; HNF1A; GATA1; CRTC1; TSHZ2; TULP1; ZNF550; IRF6; POU6F2; E2F4; CHD2; ALX4; ZNF141; EMX1; SCAI; RFX2; ZNF814; MED25; ATN1; TFAP2A; RBFOX2; CNOT3; KMT2D; PROP1; OVOL2; SSBP3; HSF4; TAF4B; NEUROD6; TEF; TFDP3; RORB; CBX4; HDAC5; NR1I3; ZNF345; PDX1; ZNF671; NR6A1; ERBB4; ZNF771; ALX3; TLX3; ARNT2; DOT1L; MYCL; ZNF225; ZNF471; VGLL1; ZNF155; HNF4A; ZNF264; ATF7; ZNF391; TAL1; VENTX; HOXD1; FOXB1; ZNF221; MAP3K10; TDP2; ZNF75D; ZNF665; ZNF544; HINFP; LYL1; RBPJL; SALL2; HDAC9; ESRRG; SOX18; AIRE; GBX2; NEUROG2; CARF; ZNF132; RORC; CDX4; ZNF224; PRDM9; HOXB1; SOX5; ZFP2; SSX7; TP73; NOC2L; POU4F3; ZNF480; SCRT1; LIN28A; CBX2; NEUROD2; TUB; ZNF215; ZNF606; ZNF407; SOX3; ZNF500; PAX6; LZTR1; SOHLH2; HNF4G; SP4; SPI1; RAX; ZNF701; ZNF10; ZKSCAN4; ZNF214; PAWR; KLF8; ZNF711; KLF15; ASH1L; BRDT; SOX13; MAK; PAX3; ZNF749; FOXD3; FOXH1; ZNF695; PAX7; EN1; HMX1; NFIX; ZNF549; GRIP1; ZNF816; ZNF778; CDX2; TCF21; SNAI2; POU2F3; SUPT3H; ZNF710; THRA; FOXI1; LDB1; ZKSCAN3; HES2; CREBL2; SUPT6H; OVOL1; FOXJ1; HDGF; MXD1; POU1F1; AEBP1; PAX4; ACTL6B; SOX1; MLLT1; DLX2; HMGA1; BNC1; NFE2; CEBPE; FOXF2; NHLH2; ZNF223; SIX3; ZIC3; HOXD3; TAF9B; ZNF135; RARG; PBX1; NHLH1; NR2E1; TBX1; TXNIP; ACTL6A; VDR; ZNF528; AR; MAPK8IP1; ZNF219; SSX3; CD3D; L3MBTL1; ZNF682; ZNF440; ZIM2; MEIS2; KLF3; ZNF611; ST18; ZNF33B; PROX1; ZFPM2; ZNF117; EHMT2; CIR1; TOX; BPTF; NEUROG1; TCEA1; MNDA; FOXA2; ZNF124; PNRC1; DCC; PKNOX2; HAND1; SUPT4H1; ZNF580; RFXANK; KLF1; CBFA2T2; EP300; DBP; HOXD13; NEUROD1; ZNF354A; NFIC; WNT4; ZNF423; ARID3B; TWIST1; ZNF232; FOXF1; MED16; C1QBP; FOXA1; NANOG; SLC2A4RG; ZBED2; PRDM2; NR1H4; POU4F2; TCF7L1; HIC2; CERS6; CNBP; ZNF175; ZNF512B; ZNF573; HIRA; TGIF2; NR1I2; CBX7; ZSCAN18; KAT2B; SP140L; ZNF623; LHX6; ZNF532; PBX2; ZMYND8; NR2F6; RNF141; DLX5; KLF11; SOX17; IRF8; KLF9; BRD4; PTRF; FOS; ZNF589; EPAS1; HHEX; NKX2-1; MECOM; CITED2; SOX11; EHF; TRPS1; PRRX1; NKX2-2; EMX2; TGFB1; INSR; SSX1; ZNF91; RSF1; ID1; SOX2; NFAT5; MAF; INSM1; GATA6; NR2F1; KLF4; PEG3; STAT4; FOXG1; KDM5D; HOXB2; POU2AF1; ZNF331; ZIC1; ESR1
Down-regulation 147 NFKBIA; HOXA5; MYC; SUV39H1; CCNA2; NFIL3; TBP; NUP62; CDK7; SOX4; XBP1; VGLL4; FHL2; BHLHE40; FOXJ3; FOSL1; ID2; EZH2; BASP1; FOXO3; EED; PUF60; BRPF1; SMAD3; ATF1; TSC22D2; MAGED1; CRK; ARID4B; ADNP; MTF2; EGR1; ZNF146; KDM2A; HOXA10; HOXC6; NRIP1; BLM; ZBTB11; CHD1; NCOA4; RBM14; CTR9; VEZF1; ZBTB1; SMAD7; TAF1D; NFIB; AFF1; TBPL1; FOSL2; ZNF443; NFKB1; ZEB2; USP22; REST; EDF1; RNF111; MGA; KAT6A; ING2; TRIM32; CRY1; PREB; BMI1; PATZ1; ING3; SFPQ; RBBP4; CEBPZ; SETD2; SNW1; USF2; HDAC1; ELF1; ELF5; KLF6; EGR3; JUNB; BCOR; SIAH2; FOXC1; NKX3-1; PAX8; MED6; NR2F2; MED1; HSF2; NFE2L1; TLE1; MED17; BRD3; RNF4; HTATIP2; SIM2; ZNF302; PURA; IRF7; NPAT; TAF9; SIX1; BRD8; TFAM; ZBTB18; NRBF2; UBE2I; CENPF; NCOR2; SAP30; PCGF2; BTG1; EGR2; FLNA; NELFB; ZNF12; KLF2; NCOA1; STAT6; CHD7; RCOR1; WWTR1; SOX9; ZBTB38; ELK3; ZNF267; TBL1XR1; RUNX3; HMGB2; JARID2; DEK; HMGN3; IRX5; RNF6; SPEN; TSC22D1; DAXX; BATF3; HLTF; SMARCA2; MYBL1; THAP11; BHLHE41; AHR; NR3C1; NFATC3; SATB1; PPARG