Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09786 Brivanib GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 54 EGR1; DNMT1; FOXO1; NR0B1; PBXIP1; HEY2; NKX3-1; EGR2; ZNF112; CBX6; MSX1; SALL2; ID4; CREB5; PAX8; ZSCAN18; TFCP2; NAB1; ZNF83; BACH2; JUN; MAFB; AES; ZNF415; HIC2; MLXIP; EGR3; SALL1; JAK2; ERBB4; NFAT5; TRPS1; ZFP36L1; EMX2; ASCL1; MAF; INSR; SOX17; LMCD1; KLF2; CEBPB; NPAS2; PITX1; TRIP6; GATA6; TLE4; MEOX2; ESR1; TRIM29; FOXG1; PEG3; HOXC6; SOX11; ABL1
Down-regulation 35 TFDP1; IRF7; NUP62; ENO1; HMGB3; ARRB1; TOB1; SP110; TDP2; ZNF148; BHLHE40; IRX5; SMAD1; NR1D2; DDX5; CD3D; ID3; FOXF2; NFIB; SMAD6; PTTG1; PDLIM1; WT1; BRD2; LITAF; NKX2-1; KLF10; TOX; SNAI2; KDM5D; ID1; SATB1; PBX3; TBX2; PPARG