Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09772 Linsitinib GSE70138 HA1E Human 24h 0.04uM EID0003
Types Number Response transcription factors
Up-regulation 63 CEBPD; GABPB1; BCL11A; CIITA; ACTL6B; TGIF1; SUPT6H; ID4; KLF11; ZFP36L2; RAD21; KDM4C; TULP3; VDR; TWIST1; BATF; FOXA2; ZNF34; ESRRG; CARHSP1; FOSL2; ST18; CEBPE; CHD8; SALL2; WNT4; INSR; WT1; CD3D; FOS; SERTAD2; ARNT2; VGLL1; TXNIP; ZNF165; ZBTB16; NFE2; LMCD1; MEIS2; ZNF516; HIRA; NEUROD1; HDAC9; TFDP2; NFE2L3; IRF9; RXRA; HLX; ZBED2; ZNF331; TBX2; MNDA; ELF3; ID3; INSM1; NR4A2; GATA6; TOX; SNAI2; MEIS1; KDM5D; ABL1; SATB1
Down-regulation 58 CRK; HMG20B; HOXA5; URI1; NRIP1; MYCBP; NPM1; ZKSCAN1; TCEA2; NFKB1; ZNF665; TDRD3; BIRC2; EDF1; AES; TTF1; NR2F2; YWHAB; CTR9; ATF4; SAP18; FOXO1; SFPQ; HOXC6; KLF2; HOXC10; TAF10; ZEB2; CITED1; CEBPG; ZNF721; HEY2; SMARCD3; ZBTB38; ZNF160; BMI1; DMTF1; MBD2; ZFP36L1; IRF7; SALL1; BTG1; NKX3-1; FOSB; IKBKAP; PBX3; TOX3; TGFB1; MEOX1; HOXD1; MAFB; FOXC1; BHLHE41; SOX11; EGR3; PPARG; GATA2; NR3C1