Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09771 Linsitinib GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 45 RELB; VGLL4; IKZF1; NFKB1; PKNOX1; TCF7; BCL3; USP16; BATF; CD3D; ARID5A; FOXD1; IL16; RUNX1; RUNX3; HIVEP2; NR3C1; PAXBP1; GFI1; TGFB1; NPAS2; ARNTL; CAMTA1; NAB1; CREBL2; SPIB; SMARCA1; NR1H4; LITAF; BCL11B; HDAC9; SHOX2; TBL1X; YBX3; TRIM29; TBX2; NR2F1; ZEB1; MNDA; ZHX2; FOXC1; ELF3; FOXG1; SNAI2; ZIC1
Down-regulation 42 HSBP1; RCOR3; HTATIP2; PGR; HMGB3; NR0B1; CENPF; AFF1; HSF2; AEBP1; GATAD2A; SAP30; HMGB2; SOHLH2; CHD7; DNMT3B; ZKSCAN1; ZBTB20; LMCD1; ZMYND8; MED1; TOX3; SIAH2; MLXIP; ZNF652; HMBOX1; OSR2; BTG1; ZFPM2; KLF10; DACH1; ZSCAN18; PTTG1; TRIM22; TXNIP; EYA1; TOB1; ZBTB16; PIR; HOXC6; SATB1; GATA2