Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09770 Linsitinib GSE70138 HA1E Human 24h 0.37uM EID0003
Types Number Response transcription factors
Up-regulation 45 HDAC6; SIM2; SSBP2; FOXD1; MXD1; TULP4; HIVEP2; EMX2; ID2; TLE4; KLF6; HSBP1; NPAS2; ERG; MYB; TAF10; KLF9; FLNA; PAX6; CBFB; ZSCAN31; POU4F1; TBX2; HOXD1; ZNF91; FOXF2; ZNF536; ZNF160; NKX2-2; WT1; TCF4; JUP; FOSL2; MEIS1; ZNF721; ZNF165; ZSCAN18; SMAD1; SPIB; TWIST1; FOXF1; GATA2; MECOM; SATB1; NFATC3
Down-regulation 34 GMNN; MTA1; TAF6; ARID1A; NFIB; ZNF532; TEAD4; TGFB1I1; RREB1; PIR; RXRA; CEBPB; FOXO1; CERS4; PIAS1; ZBTB16; NFE2L3; SP3; ZFPM2; SOX9; CD3D; BCL3; GTF3A; CREB3L2; SPEN; ZBTB18; YBX3; CALR; ID4; ZFP36L2; MSX1; SSX1; ID1; PPARG