Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09769 Linsitinib GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 32 KDM5A; EMX2; MYT1L; HLF; BLM; SMAD1; ZIC1; LHX2; NFIC; MYT1; HES1; ZNF148; BBX; CBX6; ENO1; DLX5; NKX3-1; HMGA1; CREB3L2; NFAT5; ZBTB16; KLF10; HOXB6; NKX2-2; IRX5; CRYM; NR2F1; TXNIP; GATA2; MEIS2; MEIS1; PEG3
Down-regulation 39 PUF60; MYCL; TRIM16; TFCP2; NAB1; ZMIZ2; HDAC1; NRIP1; NFE2L3; PBX3; LMCD1; FOXO1; NFATC3; KAT7; IRF8; SAP18; TCF7; JARID2; CHD7; BCL11A; TLE4; MYB; ABL1; ZNF652; GTF3A; BHLHE41; MNDA; GATA6; DACH1; PIR; AEBP1; FOXG1; MAF; TSC22D1; THAP11; LEF1; SATB1; PPARG; NR3C1