Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09768 Linsitinib GSE70138 HA1E Human 24h 3.33uM EID0003
Types Number Response transcription factors
Up-regulation 39 MNAT1; MECP2; SSBP2; NR4A1; FOS; NR1H2; HES1; MEF2A; BCL3; ZNF91; ATF3; TRIM29; NR4A3; SIX1; LPIN2; REL; ELF5; PURA; SOX10; ID4; HOXD1; ERG; PPARG; PAX6; TGFB1; MECOM; FLNA; TWIST1; NR1D2; PDLIM1; ZNF331; NR4A2; WT1; FOXC1; KLF5; ZIC1; BHLHE41; NFATC3; SATB1
Down-regulation 20 DNMT1; SUZ12; EZH2; DLX5; ZFP36L2; NFE2L1; MITF; TBX3; TFEC; AFF1; MYB; MSX1; TRIM22; TSC22D1; HOXC6; BTG1; AEBP1; GATA2; TBX2; NR3C1