Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09767 Linsitinib GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 35 MNAT1; RNF111; CNOT2; CBFB; CBX5; BLM; FOXK2; SFPQ; MECOM; SKI; HOXD3; MEF2A; RNF141; ADRB2; SMAD3; ELF1; LPIN2; NR0B1; MAGED1; PHOX2B; EYA1; TXNIP; PBX1; ZNF423; NKX3-1; ZFP36L2; HMBOX1; ZNF165; PDLIM1; IFI16; GATA2; KLF10; MEIS1; NFATC3; PEG3
Down-regulation 43 ZNF12; TTF2; MED6; TLE2; HIPK1; DNAJC1; BACH2; NKX2-1; IRF7; AES; PCGF2; MYCL; WNT4; ST18; ZNF83; ZBTB18; MYB; NFE2L3; PLAGL1; TOX3; SATB2; BNC2; IKBKAP; CITED2; MEOX1; ETS2; ELF5; SHOX2; NR1H3; BCL11A; HTATIP2; BMI1; MITF; MAFB; HHEX; FOXG1; KLF4; HEY1; ZIC1; SATB1; DACH1; ID1; PPARG