Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09766	Ruxolitinib	GSE70138	HA1E	Human	24h	0.04uM	EID0003

Response Information :

Types	Number	Response transcription factors
Up-regulation	80	TCFL5; STAT5A; ZBTB32; ZEB1; NAB1; INSR; WWTR1; PKNOX1; ZNF124; SKI; NFE2; CREB3L2; PRRX2; FOS; RBL1; HIPK3; GMEB2; SMAD5; HIC2; KLF10; E2F2; MED7; ETV5; TFDP2; KAT2B; GATA6; RXRA; RBM14; SMAD3; ZBED2; MECOM; MED6; BMI1; EGR2; HDAC4; IRF1; REST; LIMD1; TFEC; CNOT6; TXNIP; MEF2A; MYRF; ID4; NR3C1; JUNB; ZNF217; IL16; HBP1; SOX10; CBX7; ZFP36L2; ST18; CREM; TFCP2L1; BATF3; KLF6; MXI1; PIR; HOXD1; ATF3; SUB1; ID1; SMAD6; NR1D2; IFI16; ERG; DLX2; ZEB2; NPAS2; EGR3; ZBTB18; MNDA; ZNF423; TOX3; ID3; LITAF; BHLHE41; NR4A2; NFATC3
Down-regulation	61	ZNF12; DDIT3; BACH2; TRIM27; POLR3C; PFDN5; NRIP1; PSPC1; ZMIZ2; RORA; PAX5; APEX1; SREBF1; FOXM1; TEAD3; BAZ1A; CHD8; CBFB; TFCP2; COPS2; PATZ1; SUPT3H; DEAF1; ZNF354A; DDX17; FOXA1; HOXC10; TDP2; SALL1; HOXC6; NFIB; HOXC4; ELF1; SOHLH2; NR2C1; SMARCC2; GTF3A; HMGB1; THAP11; CTNNB1; ZFP36L1; ZNF91; EMX2; SPIB; SOX9; NR2F2; SATB2; ELF5; HEY1; MEIS1; FOXG1; SOX11; ZHX2; MAF; DACH1; FOXF1; POU2AF1; MEIS2; GATA2; SATB1; TBX2