Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09765 Ruxolitinib GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 53 ZNF274; KLF7; YEATS2; BACH1; BATF; MSC; RBM14; HR; PROX1; STAT2; ENY2; DPF2; HMGB3; PPP1R13L; NR1I2; ZBTB43; GFI1; HDGF; SMAD6; EN1; MEF2A; ELF1; ZNF189; MYB; ZNF552; SIAH2; KLF9; ZNF146; NFAT5; MAGED1; RUNX1; DLX5; DEK; FOXL2; RXRA; CHD7; PURA; ADRB2; PDLIM1; PEG3; MAF; TBX3; NR1D2; SNAI2; ZSCAN18; BAZ1A; ID3; PPARG; MNDA; PIR; TOX3; NFATC3; KDM5D
Down-regulation 60 PSIP1; PBXIP1; HMGN3; CHD1; ZNF593; CHD4; PHIP; RRN3; CARHSP1; NR4A2; CTBP2; PFDN5; NFIB; RCOR3; HSF2; CIZ1; BAZ2B; NR2F2; ARID1A; NR4A1; PRRX1; C1QBP; PBX3; NR2C1; CREM; HEY2; CREB5; DNMT3B; JUNB; TRIP6; MEIS2; OSR2; NR2F1; MEOX2; KLF4; CBX7; CITED2; ZBTB20; TFAP2C; TOB1; BHLHE41; CERS4; TGFB1; IKBKAP; HOXC6; SMARCA2; ZFPM2; FOXG1; ZFP36L2; BNC2; ABL1; ELF3; SOX9; ESR1; EGR3; SPIB; NFE2L3; GATA2; SATB1; TBX2