Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09763 Ruxolitinib GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 39 GATA3; AEBP1; OSR2; CBFA2T3; SSBP2; WWP1; BLZF1; IRF8; POU2AF1; FOXO1; LYL1; ELF4; ZNF107; REL; PAX5; HTATIP2; LMCD1; ZNF652; PCGF2; TBX3; CBX7; PIR; PPARG; ESR1; ID1; NFE2L3; TXNIP; ZNF91; MYRF; MITF; HHEX; NPAS2; ZNF423; ID3; LITAF; GATA2; SNAI2; LEF1; ABL1
Down-regulation 56 CHD3; MNT; ZNF281; NR4A3; CBX4; CCNT1; YBX1; EDF1; TAF7; FOXG1; MTDH; PAX6; ZNF512B; ZNF148; ZNF239; TAF9B; NFIB; BCL3; FOXD1; LHX2; DBP; CALR; KLF9; ZNF93; JUND; SOX11; CREB3L2; MXI1; NR1D2; FOSL2; SUB1; PDLIM1; MEIS1; KDM5D; PITX1; ZBTB18; VDR; PITX2; TOB1; TRIM32; WWTR1; PTTG1; CRY1; ZBTB38; SMARCA1; HMGN3; STAT4; JUNB; GATA6; MSX1; BHLHE41; TOX; HOXB2; SATB1; TBX2; NR3C1