Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09761 Ruxolitinib GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 56 HEY2; TCEA2; HDAC1; RXRA; SMAD3; SALL2; HDAC4; BCOR; CEBPB; BCL6; KLF4; AHR; SOX9; TXNIP; ID1; NPAT; ELF1; NR1H4; PATZ1; NR4A2; CENPB; ZNF83; ZNF580; ID3; TCF7L2; TGFB1; MAFB; SAP30; PCGF2; NCOA1; MAGED1; ZIC1; STAT6; TRIP6; BRD3; NAB1; FOSL2; ID4; REL; HEY1; ISL1; DACH1; NFE2L3; TBX2; OSR2; ZFPM2; RUNX1; EGR3; SMAD1; MAF; PBX3; SOX11; EGR2; ZNF331; ZEB1; SATB1
Down-regulation 32 RFX5; TGFB1I1; KLF7; COPS2; BATF3; ATF3; CENPF; RNF6; TCF21; ETV5; RORA; CREB3L2; WT1; BBX; PLAGL1; YWHAB; MEIS2; WWC1; BRD2; LMCD1; FLNA; IRF4; SMARCA1; ZMYND8; ESR1; ZNF423; SOX17; HOXC6; PEG3; ADRB2; GATA2; PPARG