Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09759 Alpelisib GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 37 NFKBIB; ZNF274; HOXA6; MXD3; IFI16; SNAI1; LYL1; POU4F1; BATF; E2F2; HR; ONECUT2; NR0B1; POU2F2; IRF2; ZBTB16; WNT4; NR1H4; NFIC; CITED1; NKX2-1; FLI1; SOX10; MBD2; EYA1; SOX11; ZBTB20; TAL1; TXNIP; PTTG1; ELK3; YBX3; ZNF91; POU2AF1; MAFB; ESR1; ABL1
Down-regulation 38 ZNF394; DDIT3; ETS2; NRIP1; NR2F1; TDP2; BCL10; SLC2A4RG; PIR; RYBP; IRF8; CREM; HMGA1; TRPS1; ZNF165; PBX3; ISL1; HLX; EHF; TBX3; AHR; MAF; FOXF1; TOB1; KLF5; ZNF331; TRIP6; TOX; HEY1; HOXC10; MEIS1; TSC22D1; LITAF; SATB1; ID1; GATA2; TBX2; PPARG