Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09755 Alpelisib GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 28 MYC; SOX4; ARID5B; HMGA2; ARID4B; HMGB3; REPIN1; BAZ2B; ZKSCAN7; ETV5; YBX3; PAWR; TCF7L1; ZNF107; BRD3; E2F8; INSR; ZNF302; MYBL1; ZSCAN18; WWTR1; BCL11A; ERBB4; MYB; HOXC6; GATA6; POU2AF1; ABL1
Down-regulation 23 DRAP1; FOSL1; EGR1; NR4A3; ATF3; TRIM24; PQBP1; SREBF1; SSX1; WT1; HMGA1; TGFB1; AHR; PIR; KLF4; TOX3; ID1; ZNF331; MAF; SNAI2; SATB1; TBX2; PPARG