Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09754 Nvp-bez235 GSE70138 HA1E Human 24h 0.04uM EID0003
Types Number Response transcription factors
Up-regulation 85 CEBPD; MED12; MTA1; TCF7L2; EZH1; HDAC5; HDAC6; ZNF117; ING4; FOXN3; TCEA2; HMGA2; KLF7; BANP; SETDB1; EN1; ZSCAN9; FOXD1; ZNF91; HBP1; LDB1; NFYC; ZNF239; FOSL1; TGFB1I1; MAFG; ZNF83; KLF2; KLF6; DEK; SSBP2; NR3C1; VPS72; NONO; ZNF195; HOXA7; NR1H3; DDX17; FOXF2; MYBL1; PCGF3; NEUROD1; HOXD1; SERTAD2; TBL1X; JARID2; WWTR1; ZNF665; HOXC4; KLF11; PRRX2; PHOX2B; MXI1; TCEA1; LMCD1; RBPMS; HOXB2; TRPS1; PAX6; ZNF160; ZEB1; HMBOX1; ARNT2; YBX3; HOXC6; CITED2; STAT4; ERBB4; ASCL1; INSM1; ZFP36L1; SIX2; TGIF1; HOXB7; HOXC10; SMARCA1; PAX5; NFATC3; LITAF; PBX3; FOXG1; MEIS2; TOX; PEG3; ABL1
Down-regulation 56 XBP1; MYCBP; GTF2A2; TCF4; CUX2; RFX5; NFIL3; AFF1; MNAT1; MTDH; PREB; CHD3; DMTF1; POLR2A; TBPL1; HIPK1; SFPQ; MAGED1; UBP1; TAF9; PAX8; TRIM16; SALL1; FOSL2; SUB1; SIAH2; PIAS2; BHLHE40; BCL11B; CCNC; VDR; HLF; PTRF; YWHAB; CRY1; MKL2; LEF1; JUNB; MYB; ETS2; IRF8; SOX17; ZBED2; ZFP36L2; BRD2; MSX1; ZBTB38; HIRA; PIR; ZBTB18; SATB1; TBX3; FOSB; ID1; GATA2; TBX2