Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09753 Nvp-bez235 GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 120 HBP1; MTA1; FOXO4; EZH1; SAFB; CRTC1; BTF3; ZNF219; CAPN15; ING4; CALCOCO1; PPP1R13L; HDAC5; SIRT2; SETDB1; NONO; BANP; MAFF; TCF25; HOXC11; MNT; ARID4A; TCEA2; MXD3; GTF2IRD1; KDM5C; HMGB3; SNW1; HMX1; HDAC7; PNRC1; CEBPB; FOXN3; HMGA2; ZNF768; HR; HINFP; MAP3K10; UBE2B; MEF2D; KLF13; PRDM1; HOXD13; ZBTB16; TCF20; TGIF1; BRD3; SKI; MED15; NPM1; CBFA2T2; JUP; MLXIPL; CRYM; PQBP1; TCEB2; BAZ1B; DDX17; NFIC; JUND; BRD8; PAX6; IRX4; FOSL1; HOXC4; PFDN5; KLF11; SPI1; HDAC9; ZNF423; BRIP1; SIX3; KLF3; CBX7; ATF4; TDP2; TCF7L1; ZBED1; LHX6; ZNF302; SOHLH2; HOXB13; TBL1XR1; IFI16; NR1I2; NR4A1; PHF20; RBPMS; UBE2I; ZNF117; TRIP6; MXI1; CARHSP1; NKX2-1; INSM1; TCEA1; ETV4; TFDP2; HMGA1; YBX3; TLE2; POU4F1; TXNIP; AFF1; FOXG1; NEUROD1; ST18; ZNF532; INSR; KLF9; TSC22D1; HOXD1; BTG1; IRF8; ATF3; SSX1; AHR; ELF3; NFATC3; ABL1
Down-regulation 53 HOXA5; GTF2A2; MYCBP; LOXL2; XBP1; NFKBIA; HOXB6; DR1; WDR77; RUVBL1; RFX5; MAGED1; SFPQ; HEY1; RNF111; PAX8; CREB3L2; HOXB5; ZNF652; ESRRG; BRD2; MSX1; SIAH2; MTF2; SIM2; TRIM16; GATAD2A; RUNX1; JUNB; TOX3; LEF1; HOXB2; RNF6; MED21; CEBPG; FOSL2; HOXB7; IKBKAP; ID3; MBD2; RYBP; BMI1; MYCN; ELF5; NR2F1; SMARCA1; PEG3; MECOM; SATB1; MEIS1; GATA2; TBX2; PPARG