Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09749 Nvp-bez235 GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 101 VGLL4; MTA1; FOXO4; ZNF408; ING4; TCEA2; HBP1; MYC; LZTR1; HDAC5; EZH1; HDAC6; ZNF83; CDK7; ATF4; CALCOCO1; KLF11; DDIT3; MAFF; PBXIP1; TCF25; NR2C1; FOXN3; PHIP; CIZ1; ARID4A; TGIF1; ZNF358; ZNF32; ELF2; ZNF529; ZNF195; ZNF112; FOXD1; PQBP1; HMGA2; ZNF219; NR2E1; FOS; HINFP; ZNF85; ZNF33B; USF2; CEBPB; TDRD3; ZNF43; MNT; TRIP6; INSR; ZNF345; CIR1; ZNF227; TTF1; CBX7; TSC22D4; ARID5A; ZNF302; ZBTB16; TCF7L2; HTATIP2; HMGA1; ZNF117; TCF15; APEX1; KLF2; PFDN5; YBX3; KLF6; MEOX2; ZNF91; LHX2; ZNF415; LPIN2; KMT2A; UBE2B; SP100; SOHLH2; ZNF93; EN1; HES1; SMARCC2; NR1I2; FOXG1; TLE2; FOXA1; CREBL2; NR3C2; NR1H3; ZBED1; PPARG; TCF7L1; FOSB; ID1; ZNF331; MXI1; AEBP1; NR4A2; BTG1; SOX11; KDM5D; ABL1
Down-regulation 50 MYCBP; XBP1; CCNA2; GTF2A2; NFKBIA; RUVBL1; BHLHE40; NUP62; PREB; NFIL3; RNF111; WT1; SFPQ; DR1; PAX8; TRIM16; PLAGL2; WWC1; ING2; ZBED2; VEZF1; ASH2L; MAGED1; NR2F1; MYCN; MEIS1; CBFB; PTRF; RAN; EYA1; GATA6; SMARCA1; VDR; TCF4; SUB1; ZNF652; TCF21; ZBTB38; NKX3-1; TOX3; PITX1; ESR1; IRF4; MEIS2; LEF1; PEG3; SATB1; ZBTB18; SSBP2; TBX2