Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09716 Plx-4720 GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 49 KAT6A; TBL1XR1; TCF4; BRD8; ACTL6A; FLI1; EGR1; HIPK3; ELK3; CNOT6; RBBP4; UBE2B; ZNF266; IRF2; FOXO1; FOSL2; SMARCD3; RERE; BAZ2B; RNF14; DAXX; BHLHE41; CHD7; RUNX1; IFI16; ZBED2; CEBPZ; TSC22D1; STAT3; MAGED1; E2F5; WWC1; NFE2; SUB1; PRKDC; CITED1; TRIP6; ZNF532; NPAS2; MECOM; SOX9; ZBTB18; TRPS1; MYRF; ID4; TRIM29; ZEB1; EGR3; TFAP2C
Down-regulation 66 TLE1; FOXN3; KLF11; HNRNPD; PSIP1; SMARCB1; MSC; KDM4C; HMGB2; LIN28A; PRDM10; DDX17; FOXM1; NANOG; EGR4; FOXD1; KLF4; FOSL1; RNF138; EN1; ESRRG; XRCC6; CD3D; APEX1; CREB3L1; ZNF423; OSR2; NFATC3; FOXF1; ZNF281; DBP; IRF6; SALL1; MED1; DNMT3B; PITX2; HLF; BCL11B; TCF21; HOXB6; ENO1; CARHSP1; FOXG1; NR5A2; SATB2; RYBP; TOX; PITX1; MEOX2; MYBL1; PBX1; BAZ1A; PBX3; FLNA; ID3; HEY1; GATA6; ZNF91; NR2F2; SATB1; AHR; PEG3; GATA2; TBX2; ADRB2; PPARG