Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09710 Pf-477736 GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 54 NFKBIA; MNAT1; EGR1; RELB; ATF3; ZNF211; ATF4; NRBF2; EGR2; CEBPA; ETV5; MAFF; PLAGL2; CEBPB; ZNF410; TRIB3; FOXM1; ZNF45; TOB1; DDIT3; BATF; CREG1; JUNB; RUNX3; TGFB1; YBX3; SERTAD2; TSC22D3; HOXA1; ZNF232; KLF4; STAT1; HES1; ST18; IRF1; BRD2; FOS; KAT6B; DDX5; SOX9; ZBTB16; BATF3; ID1; RUNX1; TP63; PEG3; TOX; TRIM22; TWIST1; SNAI2; ARNT2; BHLHE41; MAFB; KDM5D
Down-regulation 57 TBL1XR1; AFF1; SMAD4; NRIP1; MAGED1; SFPQ; CHD7; JARID2; PAX8; NR3C2; CHD1; RREB1; ZHX2; FOSL2; MYT1L; ID4; ZNF292; TBL1X; REPIN1; CTBP2; ZBTB18; MTF2; BAZ2B; MYCL; HOXC10; TGIF1; AR; ING3; ERBB4; HOXC4; ZNF107; HOXA10; BRD3; RLF; KLF6; HMGB1; TXNIP; PRKDC; ZEB2; TCF4; SALL1; CERS6; ZBTB20; HOXB7; SATB2; AEBP1; MXI1; ASCL1; WT1; HOXC6; MITF; ABL1; SATB1; DACH1; ESR1; TBX2; PPARG