Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09701 Roscovitine GSE70138 HA1E Human 24h 0.04uM EID0003
Types Number Response transcription factors
Up-regulation 18 KAT6A; SOX4; MAFF; IRF1; MAGED1; JUND; SP110; RUNX1; STAT1; FOXO1; TSC22D1; JUNB; MYRF; TXNIP; HTATIP2; MITF; ZFP36L1; ABL1
Down-regulation 28 PROX1; ENO1; ESRRG; CUX2; RAN; PITX2; ZNF281; ID3; JARID2; HOXB6; NR1I2; PDLIM1; CREB3L2; ZEB2; HOXC10; STAT4; MYCN; ZNF423; SMAD7; MNDA; MXI1; LITAF; ERBB4; SATB1; DACH1; PPARG; TBX2; GATA2