Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09698 Roscovitine GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 44 NKX2-2; ZMYND11; NCOA3; RCOR1; JUNB; ETS2; ESR1; PURA; ZSCAN31; KLF6; ZNF443; SIM2; ZNF165; NR1D2; MED1; CBFA2T3; CBX6; GATA6; HTATIP2; RUNX3; PAX6; CITED2; NAB1; TOPORS; WWC1; WT1; ZSCAN18; BRD2; STAT3; NR1H3; TLE2; CTBP2; TAL1; IRF8; MITF; TXNIP; MYB; HOXB2; IRX5; GATA2; ASCL1; DACH1; TOX3; SATB1
Down-regulation 47 LZTS1; ID3; NRIP1; ZNF593; SCMH1; ZNF423; PFDN5; MED24; NR2E1; COPS2; KLF7; TCF7L1; RBPJ; ZFP36L2; ETV5; APEX1; TBL1X; PQBP1; TRIM22; ZNF22; KDM5D; FOXG1; POU5F1B; YBX3; ERBB2; POU2AF1; PBX3; SIX2; SMAD6; STAT4; PIR; NFIB; ZBED2; ABL1; SNAI2; ZEB1; ELF5; NANOG; MEOX2; ARNT2; TRIP6; ZFPM2; MEIS2; ID1; ADRB2; PPARG; TBX2