Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09696	Roscovitine	GSE70138	HA1E	Human	24h	10uM	EID0003

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	TCEA2; ZNF544; IRF3; ZBTB48; THAP7; LZTR1; MZF1; SAP130; ZMIZ2; PIAS4; SNAPC4; FOXM1; E4F1; SPDEF; MEF2C; ZNF629; ZNF580; SUPT5H; RERE; HMG20B; CCNE1; HDAC9; RBFOX2; CALCOCO1; SOX12; MED15; EHMT2; ZNF444; ZNF83; NKX3-2; THAP10; CNOT2; MED16; TCF25; AR; RFXANK; TEAD4; NELFB; NR1H4; ZNF329; HOXA11; PCGF2; KLF11; PBX1; OVOL2; CBX6; CBX7; SAP18; HDAC4; CEBPZ; REPIN1; RUVBL2; NR1H3; SCAND1; CBFA2T3; MYCL; NR0B1; FOSB; FOS; ERBB4; JUP; TRIM28; UBE2L3; SIX2; NKX3-1; ERBB2; NPAS2; BRD3; CRYM; SALL1; HMGA1; ISL1; MYRF; LIN28A; ZSCAN18; TFEB; THAP11; INSR; MEIS2; NKX2-2; SOX9; NANOG; ESR1; OSR2; ELF3; SOX17; KDM5D; FOXG1; ABL1
Down-regulation	93	CRK; NFKBIA; TFDP1; ATF1; CCNA2; MYC; RHOA; GTF2A2; SMAD4; NPM1; ETS1; NFIL3; HSBP1; MED6; ID2; GABPB1; VEZF1; RELB; SMAD5; RBBP4; ZMYND11; KLF7; KLF6; XBP1; PEX2; MNAT1; NFKB1; ENY2; TCERG1; C1QBP; MLLT10; HIPK3; ZKSCAN1; NFYA; E2F5; RAN; UBE2B; RNF14; SFPQ; CREBZF; ZNF281; ETS2; REL; SMARCA5; ILF2; BHLHE40; TAF9B; STAT3; TSC22D2; KLF9; PURA; MED1; CCNC; CNOT6; ID4; ZNF430; YWHAB; TCF12; TOX3; ENO1; MYCN; HBP1; NFATC3; LMCD1; ERG; BAZ1A; NFIB; ZNF652; RNF138; ID3; HMGB1; BTG1; FOXO1; MBD2; VDR; LITAF; FOXA2; SNAI2; EGR3; TRIM22; IRF4; RUNX1; LEF1; AHR; NKX2-1; FLNA; IRX5; MSX1; MXI1; PBX3; SATB1; PPARG; NR3C1