Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09695 Torin-2 GSE70138 HA1E Human 24h 0.04uM EID0003
Types Number Response transcription factors
Up-regulation 60 MYC; MTA1; HMGA2; SOX4; TCEA2; HDAC5; ING4; HOXA5; EZH1; TCF25; ZNF500; DDX17; ZNF345; CREBL2; ZNF83; FOXN3; NR1H3; CARF; BCL6; BTF3; ZNF85; JUP; ZNF93; TCF7L1; TCF7L2; APEX1; MDM4; ZNF43; ZNF266; YBX3; ZNF33B; KLF11; NR2C1; NR1H4; HMGB2; SALL1; MAFF; BAZ2B; ZNF232; ZNF430; HMGB3; ZNF91; HMGA1; INSR; PAX6; ATF4; ZNF117; ST18; BACH2; HOXA10; TCEA1; NEUROD1; INSM1; ZNF264; HOXD1; FOXG1; ARNT2; SOX11; KDM5D; ABL1
Down-regulation 25 XBP1; MYCBP; BHLHE40; PLAGL2; MAGED1; PAX8; NFATC3; LEF1; YWHAB; ELF1; SIAH2; WT1; ENO1; TRIM16; HOXC10; CREB3L2; TGFB1; PIR; JUNB; MYCN; DACH1; PEG3; PPARG; TBX2; GATA2