Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09694 Torin-2 GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 249 CEBPD; KLF11; HSF1; TCEA2; ZBTB48; ZNF74; TRIB3; ING4; ZNF227; ZNF232; ZNF222; ZNF688; TERF2; ZNF500; PIAS4; PBXIP1; CCNH; SPDEF; ZNF354A; NFE2L1; HDAC6; ZNF219; ETV5; HMGA2; BCL11A; INSR; CDX1; MZF1; HBP1; HDAC5; THAP7; ARNT2; CBX7; PNRC1; ZNF75D; HIC2; CALCOCO1; SETDB1; TCF7L1; ZNF623; ZFHX3; ZNF235; ESRRA; SSBP3; SIX3; CBX4; DDIT3; MYCL; ARID3B; ZKSCAN4; KLF7; HDAC11; PPARA; PCGF1; TSHZ2; SRCAP; LYL1; MECP2; NKX3-2; TP73; ZNF34; HDAC9; RAX; ZNF345; DLX5; KLF13; HOXC5; EMX2; SHOX; SNAPC4; ZNF195; CHD2; SIX6; AIP; TCF7L2; IRF6; ZNF224; RAD21; ZNF83; ZNF778; THRA; ZNF273; ZKSCAN7; RING1; ZNF180; ZNF133; ETV6; CARF; ZFP36L2; TAF6L; HOXB5; PRRX1; EZH1; ZNF45; HOXD1; NFATC4; NR2E1; ZBTB16; PHIP; PRDM14; ZNF264; ZNF358; POLR3C; SMARCB1; ARID1A; HOXD13; ZNF573; ZNF32; ZNF529; ZNF43; ZSCAN9; HESX1; DLX4; THRB; CREBL2; USP21; CDIP1; LHX3; GCFC2; ATN1; HOXC4; ZNF394; HINFP; GATA1; TCF25; TCF20; AGO2; PEX2; PFDN5; ERBB4; RBFOX2; TFCP2L1; CAMTA1; CBX6; ATOH1; ZNF223; MNDA; ZNF423; TWIST1; NFYB; ZNF177; ZNF580; HDAC4; ZNF7; GTF2F1; ZNF263; CAMTA2; TAL1; PAX6; CEBPE; FOXG1; SALL2; ZNF124; DBP; PAX5; HOXA11; TDP2; SOX3; ZNF415; CBFA2T2; ZNF544; FOXN3; EPAS1; HOXD3; TFDP2; EP300; ZNF665; TOX; CTBP2; PRDM10; PRDM2; ZNF112; THAP10; ZNF93; ZNF3; SOX17; MXI1; TFCP2; CUX2; PBX2; BARX1; AEBP1; SOX13; MED14; MYRF; SALL1; ATF4; ISL1; MEIS2; PHOX2B; RUNX3; CEBPG; TCF7; KLF3; ZNF711; KLF9; FOXA2; ZNF467; NR1H2; TULP3; ZNF12; REL; NR1H4; INSM1; HMGA1; MLXIP; DLX2; MEOX2; FOXF2; ST18; ZNF536; ZNF117; MECOM; EHF; LIN28A; ZKSCAN1; TCEA1; EN1; NPAS2; NR3C2; ZNF175; VDR; HOXB13; KLF4; TCEB2; RBPJ; ZNF22; ZNF91; ZSCAN18; CEBPB; EYA1; MSX1; ZBTB20; CREM; HOXB2; ZNF331; TLE4; HOXB7; SPIB; HOXB6; GATA6; TRPS1; BTG1; ZEB1; HIRA; GATA2; SOX11; MEIS1; ABL1
Down-regulation 74 XBP1; MYCBP; NFKBIA; SFPQ; CCNA2; TFDP1; GTF2A2; BHLHE40; NEDD8; MAGED1; NRIP1; MNAT1; ELF1; ENO1; DR1; HNRNPD; RHOA; HDAC1; TRIM16; NFIL3; NUP62; SUB1; PDLIM1; CTR9; IRF7; TEAD1; EDF1; RBM14; PAX8; KLF6; VEZF1; PTRF; WWC1; BMI1; SIAH2; NCOA4; RNF10; NFIB; FLNA; YWHAB; PIAS2; HLF; CRY1; CREB3L2; ID4; DDX5; SMARCE1; KLF2; ZSCAN31; CBFB; BCL3; AFF1; HLTF; JARID2; STAT3; BBX; TRIP6; HOXC10; ETS2; TRIM29; RBPMS; NR2F1; BAZ1A; IRX5; EGR3; MEOX1; TBX3; NKX3-1; TOX3; ZIC1; ZBTB18; SATB1; KDM5D; PPARG