Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09693 Torin-2 GSE70138 HA1E Human 24h 0.37uM EID0003
Types Number Response transcription factors
Up-regulation 102 FOXO4; BANP; KDM5A; DDIT3; SETDB1; MTA1; ING4; MED15; TCEA2; HSF1; CNOT2; THAP7; EZH1; BRD8; ZNF500; ZNF32; PMS1; ZNF195; ZNF85; TRIB3; HMGA2; SOX4; CALCOCO1; ZNF16; ZNF23; TULP3; ZNF268; ZNF84; FOXM1; ZNF443; TCF25; ZNF544; SIN3B; ZNF573; HINFP; ZNF354A; ZNF91; ATF4; ZNF692; ZNF266; ZNF44; PCGF3; ZNF7; SKI; ZNF45; TDP2; HMGB3; ZNF184; ZNF623; ZNF219; ZNF432; ZNF232; SAFB2; KLF13; PQBP1; ZNF43; HBP1; ZNF12; TCF7; LYL1; NR2C1; CTBP2; ZNF302; ETV5; HIC2; THAP10; MTF2; BAZ2B; TERF1; TGIF1; ARNT2; ZNF264; UBE2B; ZNF217; CREBL2; ZBTB20; PHF20; FOXF2; CEBPB; HMGA1; TXNIP; INSR; BCL11A; RUNX3; PAX6; BRD4; ZNF160; NFAT5; ZKSCAN1; HTATIP2; PBX1; INSM1; MEIS2; ZNF721; FOXG1; ZBTB16; IRF8; ZSCAN18; TWIST1; MYBL1; MYRF; ABL1
Down-regulation 51 NFKBIA; MYCBP; XBP1; GTF2A2; NUP62; RUVBL1; PAX8; TRIM16; KDM2A; BHLHE40; NFKB1; PREB; URI1; GATAD2A; HIPK3; ANKRD1; ELF1; YWHAB; SFPQ; C1QBP; CALR; RUNX1; MBD2; ENO1; TBL1XR1; SERTAD2; BHLHE41; FOXL2; NLK; TOX3; MAGED1; TRIM29; SUB1; ASH2L; PTRF; FOSL2; NR2F1; CREB3L2; BMI1; ESR1; HEY1; HOXC10; PIR; SNAI2; LEF1; RBPMS; NR4A2; SATB1; HOXC6; PPARG; TBX2