Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09692 Torin-2 GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 87 FOXO4; HDAC6; DDIT3; HDAC5; EGR1; ATF4; ZNF688; EZH1; ZNF195; TCEA2; CALCOCO1; ING4; HMGA2; MZF1; BRD8; EZH2; KLF13; DEAF1; PCGF1; ZNF211; CDK7; ZNF83; ZBTB48; HMG20B; ZNF23; SOX4; USP21; ZNF419; IRF7; FOXG1; SIN3B; PBXIP1; TGIF1; ZMIZ2; KLF7; PNRC1; LDB1; TRIB3; NR2C1; NR2E1; TCF25; SP100; TDRD3; HBP1; CEBPB; TAF10; EHMT2; LYL1; CBFA2T2; TDP2; RNF10; ZBTB16; ARNTL; MED24; TRIM28; PRDM2; SUPT4H1; HOXC4; HMGB2; SAP18; CIZ1; ZNF354A; CBX7; ZMIZ1; NR4A1; DMTF1; INSR; YBX3; FOXO1; TSC22D3; SMARCD3; HMGA1; UBE2B; ZNF117; HOXC6; SMARCC2; HTATIP2; TCF7; BRD4; TRIP6; BRD2; FOXF2; TRIM22; TBX2; SOX9; TRPS1; ABL1
Down-regulation 65 MYCBP; NFKBIA; GTF2A2; PARP1; XBP1; PAX8; RUVBL1; NFKB1; BHLHE40; HIPK3; TRIM16; TEAD1; MAGED1; SFPQ; WDR77; PTRF; CALR; HIPK1; PDLIM1; EHF; RUNX1; GATAD2A; MTDH; TOX3; ENO1; MYCN; ZNF512B; CDYL; DNAJC1; ELK3; FOXE1; TRIM29; FOSL2; TGIF2; HOXB6; SMARCA2; TSC22D2; SOX13; BAZ1A; REL; MBD2; CREB3L2; WWC1; TCF4; TFAP2C; MEIS2; ETS2; RBPMS; PIR; ZBED2; NFE2L3; HHEX; ELF5; BMI1; MEOX1; MITF; SSX1; HIRA; HOXC10; LEF1; HEY1; SATB1; WT1; PEG3; PPARG