Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09691 Torin-2 GSE70138 HA1E Human 24h 3.33uM EID0003
Types Number Response transcription factors
Up-regulation 158 FOXO4; DDIT3; EZH1; PSMD9; PMS1; SETDB1; PSPC1; CALCOCO1; MZF1; CITED2; SIRT7; MTA1; HBP1; KAT2A; ZNF688; ZNF76; PAXBP1; ATF4; ZNF266; HDAC5; HMGA2; ZMIZ2; CEBPD; ING4; NR2C1; CRTC1; BLM; ZNF500; LZTR1; ZNF276; BRD8; PCGF1; ZNF211; EZH2; ZNF32; PHIP; ZNF227; ZNF195; HINFP; TGIF1; LYL1; SNAPC4; DMTF1; SAFB; KLF13; GCFC2; SOX4; FUBP1; TCEA2; SRCAP; ZNF551; MAFF; ZNF83; CDK9; CXXC1; PSMC3IP; ZNF232; IRF3; CNOT2; CAMTA2; CEBPB; ZNF23; ZNF84; LDB1; CAPN15; PPP1R13L; PIAS4; SUPT4H1; ZKSCAN1; ZNF358; ZNF544; JUP; MAFB; MED15; CBFA2T2; SIN3B; ZNF177; CBX4; ZNF692; PHF1; RNF10; ZBTB43; TSC22D3; CIZ1; ARID3B; ZNF224; SSBP3; ZNF593; FOXF2; ZNF33B; ZNF175; ARID4A; TULP4; TCF25; ZNF12; TWIST1; PRDM1; ZNF45; SUPT3H; KLF11; ETV5; VPS72; TFCP2; BTAF1; EN1; MYRF; NPAS2; BTG1; HDAC9; UBE2B; HOXC4; ETV4; ARNT2; KLF3; TOB1; BAZ2B; FLI1; CBX7; JAK2; VGLL1; BRD3; INSM1; SALL2; TBX21; ARNTL2; KLF6; ZNF573; NANOG; TULP3; HIC2; ZNF665; ZNF117; ZNF423; ZBTB20; HMGA1; LIN28A; ZBTB16; MED13; ZNF91; NFE2; ST18; NR1H3; NEUROD1; KLF5; TBX3; INSR; MXI1; POU2AF1; TAL1; BRD2; KLF2; ATF3; ERBB4; HHEX; ZFPM2; MYB; TRIP6; HOXC6
Down-regulation 84 PUF60; NFKBIA; MYCBP; GTF2A2; PARP1; MAGED1; XBP1; GABPB1; RUVBL1; RFX5; MNAT1; NFKB1; BHLHE40; SFPQ; PAX8; URI1; CBFB; HNRNPD; CHD7; DR1; HEY1; ING2; RBBP7; CREB3L1; YWHAB; MBD2; MTDH; RELA; ENO1; TBPL1; TRIM16; SMAD7; LMCD1; TSC22D2; SMARCA5; FOXJ3; PIAS2; TCF4; SIX1; SERTAD2; SIAH2; TBL1X; REST; ZNF512B; PIAS3; E2F5; AGO2; TRIM32; CUX1; GATAD2A; C1QBP; ID3; IRX5; PIR; RUNX1; BAZ1A; YBX1; LEF1; WT1; EYA2; PLAGL1; ETS2; SMAD1; HMGN3; PITX1; ELK3; SMARCA1; REPIN1; ZFHX4; SOX11; ZBTB38; ZBTB18; EMX2; RBPMS; FOXG1; LITAF; ID4; MSX1; DACH1; MEIS2; SATB1; NR3C1; GATA2; PPARG