Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09690 Torin-2 GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 207 SUV39H1; DDIT3; FOXO4; PMS1; SOX4; BANP; EZH1; VGLL4; SETDB1; ZXDC; CEBPD; ZNF408; JUP; BRD8; PSPC1; ZNF202; ZNF76; RXRB; KAT2A; TERF2; TRIB3; PSMD9; IRF3; TAF1C; SIX6; HBP1; HINFP; SND1; MZF1; MED12; HDAC6; E4F1; ZNF500; PHIP; ZNF117; HDAC5; TCEA2; ZBTB48; SIRT7; KDM5C; PAXBP1; ATF4; LZTR1; POLR3C; CEBPB; HSF4; TDP2; ZNF23; HMGA1; TSC22D3; ZNF544; ING4; PCGF1; CAPN15; TDRD3; RBM39; SP100; ZNF335; PRDM4; HDAC9; HMGXB3; CBFA2T2; HSF1; LDB1; ZNF266; SAP18; LYL1; DMTF1; ZNF84; CHD3; ZNF419; EHMT2; HOXD1; SP110; GCFC2; ZZZ3; HOXA5; ZBTB17; CALCOCO1; CBX4; ZKSCAN4; NR2C1; ZNF573; ZNF692; HOXC4; MMS19; CIC; CXXC1; THAP7; ARNTL; STAT2; KMT2B; MED15; ZNF24; KLF13; FUBP1; GTF2F1; ZNF211; NCOA2; SUPT6H; ZNF85; HMX1; ZNF224; TGIF1; IRF7; TSC22D4; POU4F1; ZSCAN16; MAFG; TAF5; ZNF74; ZNF195; USP21; ZNF611; ZNF33B; MTF2; KDM4C; PNRC1; PIAS4; TRIM27; NEUROD6; TCF7; BTAF1; STAT1; BLM; TOB1; KAT8; PRPF6; PRMT2; BTG1; SIN3B; PRDM2; MYBL1; HDAC7; CEBPG; TSC22D1; DLX5; CIR1; PFDN5; LPIN2; ZNF281; ZNF133; TCF25; ARNT2; GTF2IRD1; VPS72; SMAD3; FOXM1; TCEA1; RNF141; SSBP3; CDK9; TFAP2A; AES; MXI1; ZNF131; IRF9; UBE2B; AATF; PHF1; BRD2; ZNF83; GTF3A; PAX5; HOXA1; KLF9; KLF2; ZNF189; ERBB4; DLX4; ZNF665; HOXB7; ZNF430; NR1H3; TGFB1; ZNF302; TBX21; PIAS1; COPS5; KLF5; KLF6; TERF1; ELF3; HOXB13; EN1; ZNF107; NEUROD1; SREBF1; TRIM22; ZNF91; SMARCC2; BCL11A; PAX6; JUNB; YBX3; ZNF160; ETV4; MYB; NKX2-2; IFI16; NPAS2; ZNF721; HTATIP2; FOXG1; TWIST1; MECOM; ZNF423
Down-regulation 120 MYCBP; NFKBIA; GTF2A2; PARP1; BASP1; GABPB1; YAP1; CCNA2; TFDP1; ATF6; CREB3L2; PAX8; XBP1; HIPK3; MNAT1; REST; MAGED1; CUX1; TSC22D2; SUB1; RBM14; SMARCA5; SIAH2; TRIM16; ZFP36L1; SRF; IRF4; ZBED2; MTDH; GATAD2A; ZNF512B; NFKB1; MED6; ZBTB1; NR4A3; SERTAD2; SALL1; ILF2; ADNP; WWTR1; USP22; TBL1XR1; RRN3; HMGN3; RBPMS; PKNOX2; HOXA10; CREB3L1; ZMYND11; ZBTB38; SFPQ; MKL2; DR1; ID3; ING2; PTRF; DNAJC1; TBPL1; FOSL2; TCF4; IRF2; CBFB; TAF9B; ELK3; PBX3; PGR; MEIS2; ENO1; HSBP1; KAT6B; SMARCD3; CTBP1; CREB5; MED21; PIR; EHF; HMGB3; RUNX1; LITAF; NR2F2; PITX2; ZNF516; GATA6; FOXF1; MAF; BNC2; HEY1; JARID2; LEF1; CD3D; LMCD1; HLTF; ISL1; ID4; HHEX; TCF7L1; SHOX2; ID1; SMAD7; MITF; RXRA; WWC1; RBPJ; WT1; KLF10; SPEN; ZBTB18; MEIS1; PLAGL1; KAT2B; AHR; EYA1; EGR2; FOSB; GLI2; SATB1; PEG3; ABL1; TBX2; GATA2