Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09685 Pelitinib GSE70138 HA1E Human 24h 3.33uM EID0003
Types Number Response transcription factors
Up-regulation 40 CEBPD; KAT6A; HDAC6; ATF4; HIPK3; E2F2; TFEC; EZH1; TRIM22; BRD8; EPAS1; HMGB3; NCOA6; NFIB; ZNF589; BCL6; MED13; ZNF532; ZFHX3; CEBPB; SMARCC2; MTF2; SMAD6; SOX9; FOXC1; PHF20; DDX5; STAT1; TOB1; MECOM; ASCL1; TP63; EYA1; PIR; NR2F2; IRX5; DACH1; SATB1; ID1; KDM5D
Down-regulation 46 PBXIP1; EGR1; FOXD1; FOXN3; TCF21; LEF1; JUN; PAX8; PKNOX2; LMCD1; SIAH2; CREB3L1; RORA; ATF3; SATB2; KLF6; BHLHE40; ID4; POU2AF1; PDLIM1; NKX2-2; VDR; BHLHE41; CHD7; ID3; CREB3L2; ESR1; WT1; IRF4; ZHX2; NANOG; LIN28A; KLF10; PAX5; TFAP2C; EGR2; MAF; PEG3; HOXC6; EGR3; SNAI2; HES1; PPARG; GATA2; TBX2; ADRB2