Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09684 Pelitinib GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 218 DDIT3; ZNF274; ATF3; BANP; ID2; PCGF1; FOXO4; VGLL4; CTCF; HCFC2; ZNF23; TFE3; SIX6; ZNF273; CDC5L; MAFG; GABPB1; NFIL3; FOS; MAFF; TERF2; SIRT7; ZNF410; ATF4; ZBTB17; ING1; EN1; TAF5; CEBPD; CHD1; ZNF331; ID3; ZNF212; CIR1; ZNF141; VPS72; ZNF473; ZNF10; ZBTB11; ZNF281; ZNF263; ZNF573; NR4A3; SNW1; SMARCB1; SETDB1; ZBTB43; CEBPG; PPARD; KAT8; ZNF778; ARID4B; TAF11; NR2C2; POU2F1; CBX4; CEBPB; DMRT1; ZNF45; ZNF195; RLF; ZNF688; TGIF1; SNAI1; RBM39; KLF11; ZNF107; PFDN5; CNBP; PHF1; ZNF222; TSC22D3; CCDC59; PSPC1; EP300; EGR1; PPARGC1A; UBE2B; MSX1; BHLHE40; E2F6; BRDT; ZNF266; ARNTL; NFYC; DNAJC2; CAMTA2; RNF6; HINFP; TAF7; ZNF211; GATA1; MXD1; PRDM10; TDP2; TRIB3; SERTAD2; SAP18; CBFA2T3; LYL1; DR1; CHD2; ASXL1; KLF4; TFAP2A; FOXD1; YBX2; ZNF165; USP21; LDB1; TRIM33; BCL6; JUND; ZNF304; TFCP2L1; AIP; CNOT3; SNIP1; RORA; ZNF787; ZNF143; MXI1; NR3C1; NKRF; INSR; MED6; ZNF675; AFF4; ZNF44; TCF7L2; REL; NCOA2; PIAS1; ZNF423; TDRD3; HOXA1; KLF10; RYBP; BRD2; ZNF580; ZNF432; SKIL; ZHX2; NAB2; NR1H4; KMT2B; ZNF83; CREM; ZMYM2; VGLL1; LPIN2; PRDM2; HTATIP2; TAL1; YBX3; NEUROD1; NR4A1; ZNF117; PQBP1; NFATC1; ZNF24; BRD8; ZNF267; ZNF232; ID1; BRD4; POU2AF1; MAFB; ELF1; ERF; ASCL1; SP140; SPEN; NR0B1; HMGA1; NFAT5; OSR2; SOHLH2; BACH2; SALL1; TWIST1; FOSB; VDR; SATB2; INSM1; POU4F1; FOXF2; RBPJ; CRY1; CD3D; TCEA1; EMX2; COPS5; STAT4; BCL11B; TBL1X; PEG3; TOB1; RSF1; IRX5; ZNF91; ZMYND8; BCL11A; HDAC9; SSX1; FOXO1; HES1; ARNT2; TFDP2; IRF8; MNDA; FOXG1; HEY1; KLF5; THAP11; NFATC3; SNAI2; GATA2
Down-regulation 85 LOXL2; PARP1; RFX5; BRCA1; FHL2; SMARCC1; SMAD3; SOX4; ATF6; YAP1; MAGED1; PUF60; NRIP1; HDAC2; PRMT2; NPAT; CALR; FLNA; BRD3; RBBP7; TGFB1I1; ZNF587; TRIM16; NELFB; VEZF1; CENPB; NCOR2; TBL1XR1; STAT6; TRIM32; DNAJC1; WWTR1; HOXB6; NR2F2; PTRF; SOX9; DMTF1; RBBP4; IKBKAP; STAT1; BNC2; TRRAP; GTF2I; NR2F1; BIRC2; CREB3L1; ID4; SMAD2; TOX3; RERE; MXD4; SUB1; BAZ2B; TRIM22; ENO1; PBX3; PRKDC; ARID5B; ERBB2; ZNF652; PBX1; TGFB1; BHLHE41; MYB; ZMIZ1; NFIB; LMCD1; IRF9; NFE2L3; CCNC; GATA6; HOXC6; ZKSCAN1; CTBP2; MYCN; PLAGL1; SMARCA2; PSIP1; MEIS1; ZFPM2; ZBTB18; AHR; SATB1; TBX2; PPARG