Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09672 Tgx-221 GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 85 CEBPD; TRIB3; USP21; ZNF227; KLF11; ARNT2; SSBP2; POLR3C; THAP7; SSBP3; SPDEF; ZNF195; PBX1; NFYB; ZNF273; FOXA1; ST18; CBFA2T3; HDAC9; ZNF32; BACH2; ZNF544; TCEA1; LYL1; TDP2; SOX3; ATF4; IRF6; ZNF232; PFDN5; REL; CTBP2; NR1H4; SPIB; ZNF83; BAZ2B; SOX13; ZNF573; LIN28A; AEBP1; E2F8; CBX7; ZNF12; ZFP36L2; BCL11A; ZNF43; NEUROD1; MYB; COPS5; FOXF2; SIX2; HIC2; TFDP2; INSM1; POU4F1; UBE2L3; HIRA; SAP30; MYBL1; CERS6; NANOG; SMAD1; MNDA; TERF1; MEIS2; GATA6; OSR2; TFEC; HOXB2; TOX3; PAX5; GTF3A; FOXG1; SHOX2; ZBTB16; ZFPM2; HOXD1; TRIM22; MYRF; SOX11; MXI1; ZHX2; RBPMS; TSC22D1; TOX
Down-regulation 49 NFKBIA; TLE1; ATF6; XBP1; ZBTB38; HNRNPD; SMAD2; EGR1; CBFB; SFPQ; ENO1; ELK3; TSC22D2; ZBTB43; PAX8; BATF3; ID4; CREB3L2; MED1; BHLHE40; BMI1; SMAD3; KLF6; PIAS2; NR1D2; PDLIM1; ID3; GATAD2A; CRY1; WWTR1; FLNA; NFAT5; WWC1; TRIP6; EGR3; SALL1; BAZ1A; SMAD7; FOXC1; MAFB; TRIM29; MSX1; EGR2; SNAI2; LEF1; ID1; DACH1; PEG3; PPARG