Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09660 Cgp-60474 GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 564 CEBPD; EGR1; SPDEF; MNAT1; MEF2C; SCAI; ZNF551; ZNF235; SIX6; ZNF264; ZNF8; CARF; ZXDC; HDAC5; GBX1; THRB; MZF1; NR2E1; HIPK2; ZNF345; ZNF180; PROP1; FOS; GRHL2; ZNF154; ZNF544; ZNF814; NKX3-2; ZNF667; ZNF274; CBFA2T3; RFX1; ZNF688; MYCL; MAML3; PAX1; ONECUT1; MYC; HOXC5; ASCL3; ST18; FEZF2; MED12; HIF3A; ZKSCAN8; ZNF835; OVOL2; NHLH2; ZNF135; IRF6; DOT1L; ZNF221; PRRX1; SRY; ZNF287; ZNF136; RFX3; ZNF75D; RORB; ZNF211; SOX3; DLX5; CHD2; ZNF550; SOX5; ZNF695; ZNF223; ZNF507; ZNF10; ZNF816; MECP2; MAK; LHX3; PRDM12; NEUROD4; PPARD; ZNF117; IKZF2; ZNF391; NR1I3; POU6F2; L3MBTL1; CIITA; ZSCAN2; NR4A1; HEY2; ALX4; TAF4B; ZFY; ZNF573; ZNF394; ZNF611; ZNF225; ZNF304; ZNF484; ERBB4; HESX1; TBL1Y; ZNF471; CUX2; PRDM14; ZNF224; ASH1L; ZNF141; ZNF770; ZNF529; ZNF350; KLF11; ZNF254; MYEF2; SALL2; NEUROD6; RING1; BHLHE40; ETV1; HIVEP3; PRDM9; KLF13; ZNF711; ZNF407; ZNF557; NFKBIB; SCRT1; HOXB1; SHOX; ZNF780B; ZNF343; ZNF749; VSX1; ZBTB44; FOXD3; PRDM1; ZNF493; FOSL1; ZNF682; TCEA2; ZNF549; MYT1; POU1F1; PPARA; ZIC3; HES2; KLF8; ESR1; ZNF362; OVOL1; PAX7; HNF4A; ZNF571; TBX4; NEUROD2; ZNF440; DLX6; GCM2; E2F4; ZNF81; ZNF214; PBX1; ZKSCAN4; SRCAP; SSX7; TBX19; ATF7; TGFB1; MED31; LBX1; RBPJL; ZNF606; NOCT; NR5A1; PAX4; POU3F3; THAP9; ZNF208; POU2F3; EP300; FOXH1; AR; LZTR1; TONSL; TBX5; ZXDB; ZNF467; ZNF665; ZNF528; ZNF674; SOX17; ZNF778; TP73; CDX4; DCC; ZNF44; ZIC4; ALX3; INSR; ZNF80; EMX1; ZNF174; POU4F3; AFF2; FOXP3; NR6A1; ZNF222; SOX18; ZNF132; TEF; ZFP2; ZNF268; SOX1; PBXIP1; CBX4; SP4; TBR1; POU3F2; ZNF771; EN2; VENTX; ATF6B; RORC; SSBP3; NEUROG2; MECOM; GSC2; ZNF253; ATOH1; ASCL2; ATN1; ZSCAN9; HNF4G; CBX7; ESRRB; SNAI1; BRDT; THRA; SOX21; PAX3; CD3D; ZNF442; NR4A2; ZNF492; AIRE; MAPK8IP1; ZNF155; ZBTB48; HOXB8; PDX1; ZNF701; SHOX2; ATF3; HEYL; NFIX; TLX1; ZBTB3; INSM1; ZNF157; MYF6; THAP10; TXNIP; SOX14; ZNF85; HOXD12; CREBL2; VHL; CDX1; TBX6; ZFP69B; ETV3; LIN28A; NFATC4; ZNF273; KAT2B; PRDM2; ZNF134; TFDP3; ZNF334; MSX2; ZFHX2; E2F1; NR4A3; NEUROG3; TFEC; CDIP1; ZNF764; PAX6; ZBTB39; FOXE3; TAF6L; ING4; NHLH1; ETV2; TAF7L; TUB; WNT4; ZNF500; BCL6; HSF4; HDAC9; ZNF215; ZNF257; NR0B1; CBX8; ZSCAN32; EGR4; HOXA2; HDAC11; REL; SKI; NFE2L2; ZNF236; ZNF613; NKX2-8; ZNF556; HOXA3; ZNF112; FOXB1; MLLT1; TSHZ2; ZNF184; SIX3; ZSCAN31; HNF1A; TLX3; AEBP1; GCM1; ZNF710; BRWD1; NEUROD1; FHL5; HLF; SIX5; KMT2D; ZNF358; RAX; BCL11A; PRDM13; IKZF3; NR0B2; SKIL; AFF3; HOXD3; MAFF; ZNF580; ACTL6B; ZNF669; NKX2-2; RARG; FOXJ1; MEIS2; SPI1; ZNF480; ARID3A; PGR; IRF1; ZFPM2; ZNF415; ZNF234; LDB1; PRDM5; SP140L; TULP1; EHMT2; ZNF43; OLIG2; FOXF1; ZNF219; E4F1; KLF15; ZNF227; ZBTB7C; CBX2; ELK4; CEBPA; GBX2; FOXA2; TFAP2A; TRIB3; KDM4C; SUPT3H; ZNF426; CRX; MSX1; EMX2; FOXJ2; FOXN2; LHX6; NKX2-5; PITX1; BRF2; FOXA1; ZNF419; ZNF74; HMGA1; GRIP1; PHF1; NACA2; ZFP37; TWIST1; ZNF195; TCF7; NPAS1; NEUROG1; ESR2; ZNF675; FOXF2; SOX30; ID3; TULP2; OSR2; ZNF41; MYT1L; NR1H4; ZNF787; ZIM2; SIN3B; TRIM24; BARX1; PROX1; ZNF124; ID1; PKNOX2; PRDM10; NOC2L; DMRT1; TAL1; HBP1; ZNF444; ASCL1; ZNF91; TCEB2; POU3F4; VGLL1; NR5A2; HOXD10; GFI1; ZNF654; EVX1; ARID3B; TCF7L2; ZNF423; CAMTA2; DBP; GCFC2; ZNF286A; CREG1; ZNF34; WHSC1L1; SOHLH2; UTF1; SCMH1; POU4F2; ZNF32; LHX2; ZNF552; DLX4; HAND1; TAF9B; TCF4; ARRB1; RSF1; ZNF623; MXD4; MDM4; TAF1A; NR2C1; NKX6-1; TBX1; MDM2; HOXD1; ZNF107; ZSCAN18; SSX3; E2F5; TEAD3; ZNF93; FLI1; TCF21; STAT2; MNDA; CEBPE; CREM; TOX; HDGF; HOXD13; ZNF83; ARNTL2; ARNT2; FOXN3; PFDN5; KLF7; ZNF430; TDP2; NR1H3; TBX21; CTNNB1; KLF3; EN1; SOX13; TFDP2; ZNF536; SIM2; ZNF329; RUNX3; HOXD11; NR2F1; FOXL2; FOSB; MEOX2; MXI1; ZNF354A; ZNF331; MYRF; CNBP; CERS4; SP140; CRYM; DLX2; BACH2; HIRA; WT1; SOX2; ZNF652; HLX; TCEA1; ZNF532; CALR; KLF2; HHEX; NR1H2; BCL11B; STAT4; HEY1; TRPS1; SSX1; EYA2; PEG3; EPAS1; HIC2; GATA6; NFE2; JUNB; SALL1; KLF9; FOXG1; E2F2; BHLHE41; CERS6; MYCN; SPIB; SMAD6; ZBED2; NANOG; MAF; MYB; IKZF1; YBX3; KLF4; ZFP36L2; TBX3; ZEB1; KDM5D; NFE2L3; PIR; CEBPB; SOX11
Down-regulation 173 XBP1; FHL2; PUF60; CCNA2; HOXA5; ATF1; NUP62; BRCA1; SUV39H1; ECD; FOXO3; BASP1; TBP; HDAC2; VGLL4; NFIL3; EED; PAX8; HNRNPD; USP22; SNW1; CBX3; ADNP; EZH2; RBM14; TCERG1; TLE1; SOX4; SUZ12; SETD2; SFPQ; ING2; CDK7; BCLAF1; CNOT1; CDK2; SMARCA5; BMI1; RNF111; STAT5B; MED1; HIF1A; REST; TSC22D2; TBL1X; GTF2A2; PBRM1; HMGB2; HOXC6; ZNF146; NRBF2; SSRP1; SF1; SMAD3; NFKB1; HOXB7; ZNF410; ELF1; AFF1; UBE2I; EWSR1; CHD1; PSPC1; VEZF1; BRPF1; KAT6A; CEBPZ; SMARCD3; BRD3; ZZZ3; SMARCE1; ZBTB11; CBX5; TAF9; KAT7; ZNF148; FOXC1; TFAM; TRIM29; DPF2; ZMYM2; CENPF; RAN; RARA; SAP30; MED4; RBPMS; UBP1; GTF2IRD1; DNAJC2; DEK; PATZ1; NPAT; SMAD2; KDM2A; RNF138; NELFB; HMGB3; BLM; CRY1; NAB1; UBE3A; MAX; PURA; CDYL; DDIT3; MAGED1; RBBP4; BRD8; HMG20A; DDX17; RCOR1; IRF7; SOX9; HOXA10; GATAD2A; MED13; BAZ1A; RNF6; CTBP2; RYBP; ARID4B; CTR9; TP53; AATF; TSC22D4; FOXO1; ZNF266; ENO1; TRIM16; PTRF; TCF20; MTDH; LIMD1; WHSC1; RBPJ; HMGB1; NR2F2; EDF1; APEX1; CENPB; PQBP1; NPM1; ATF4; FOXJ3; BTG1; ERBB2; NCOA1; TRIM32; ZBTB38; ASH2L; DDX5; PCGF2; TCF12; TRIP6; SP3; YWHAB; NR2F6; DNMT3B; TLE4; HTATIP2; HOXC10; RUNX1; ELF5; NFIB; ZBTB18; PTTG1; PBX3; SMAD1; KLF10; SATB1; NR3C1; ABL1