Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09659 Cgp-60474 GSE70138 HA1E Human 24h 0.37uM EID0003
Types Number Response transcription factors
Up-regulation 516 EGR1; CEBPD; MEF2C; SPDEF; FOS; ZNF551; CIITA; HDAC5; REL; RFX1; GBX1; ZNF154; ZNF710; IRF6; ZNF688; FOXH1; ZNF467; L3MBTL1; ZNF274; ZNF544; BCL11A; MYCL; ZNF117; ZNF10; THRA; WNT4; ZNF235; SCAI; HIF3A; PROP1; ZXDC; THRB; HSF4; ZNF345; ZNF771; ZNF264; ZNF180; NKX3-2; CARF; PRDM14; ZKSCAN4; NR4A1; MZF1; NFKB2; SRCAP; CALR; OVOL2; NR4A2; SIX6; ZNF667; CUX2; RFX2; ZNF75D; ZNF814; MEIS2; MED25; PBXIP1; ZNF8; FEZF2; HOXB1; SOX17; ZNF816; HOXC5; ZNF711; HESX1; NFATC4; ZNF254; SALL2; EHMT2; MAML3; TSHZ2; SPI1; ALX4; RORB; SRY; NR2E1; AR; TGFB1; CDX1; SOX18; MAK; ZNF112; ZNF611; ZNF136; CNOT3; HEYL; ZNF571; TLX2; ZNF184; E2F4; ATF7; NEUROD4; ZBTB3; ZNF211; NKX2-5; ZKSCAN8; FOXJ1; ONECUT1; PBX1; ZNF362; FOXD3; TP73; ZNF304; ATF6B; ING4; ZNF350; HNF1A; DOT1L; ATN1; HIVEP3; RING1; SKI; ZNF682; PDX1; POU6F2; CREBL2; HNF4G; VGLL1; ESR1; TAF1; BRDT; ZNF391; ASCL3; TONSL; CHD2; GRHL2; TCF21; ZNF623; RFXAP; ZNF671; TULP1; ZFP2; CBX8; SKIL; SOX21; MBD4; TCEA2; ZNF273; ZNF695; ZNF471; ZNF224; SOX5; SCRT1; MED12; ZNF91; FOXE3; ZNF407; ATOH1; CBFA2T3; SUPT7L; TEF; ZFP69B; ZNF195; ZBTB48; KAT2A; SOX3; LIN28A; RFX3; THAP9; ZNF606; NFE2L2; ZNF76; ZSCAN31; TBX19; ZNF415; ZNF550; ZNF208; VSX1; ZBTB7B; CRTC1; ZNF225; ZSCAN2; ZNF493; ZNF835; FOXB1; TBL1Y; PRDM1; PAX1; STAT2; GATA6; ZNF135; ASH1L; TCF4; E2F5; ZFPM2; ZNF107; VENTX; ZNF665; GSC2; MECP2; HAND2; E4F1; HOXB8; HIPK2; ZNF221; POU4F3; ZNF674; RBPJL; SIN3B; TAF7L; SIX5; CBX7; RAX; CERS6; CDX4; KDM4C; HLF; PRDM9; KAT2B; BARX1; ZNF43; PAX3; PAX7; ZNF223; ISL1; PAWR; ZNF549; ZNF132; HDAC9; ETV2; GCM2; NPAS1; TAF6L; ZNF174; ZNF80; ZNF214; ZNF205; NEUROD6; LZTR1; EMX1; NR5A2; ZNF343; TBX10; ZNF334; ZNF573; KLF13; OVOL1; ALX3; JUP; TLX3; ZNF141; POU2F3; ESR2; ZNF484; NEUROG2; NR5A1; BCL6; DLX5; THAP10; MED14; ZNF232; ZNF124; ZNF500; KLF8; HDAC11; TRIM24; ZNF83; EHF; IRF3; TRIB3; PNRC1; HNF4A; ZNF331; ZNF81; ZNF701; POU3F3; AIRE; FOXF1; ZNF442; ZNF749; HAND1; ASCL2; ZNF219; ZNF780B; SOX13; SUPT3H; RORC; HSF1; LBX1; POU1F1; TCF7L2; SSBP3; NR1H4; HEY2; TCEA1; HOXA3; FOXA2; ZNF44; CBX2; JUNB; ZNF253; MDM2; TBX5; NR4A3; TLX1; SIX3; NFIX; IKZF2; TWIST1; CALCOCO1; CREM; MSX2; ZIC3; UTF1; CD3D; DCC; CDIP1; ZNF287; ZNF358; GLI3; LDB1; ZFY; SCMH1; ZNF580; MDM4; MECOM; ZNF507; CEBPZ; HBP1; SMAD5; ZNF675; LYL1; RORA; ESRRG; ZNF41; ZNF85; TAF4B; ZNF215; IRF8; AEBP1; ZNF257; ST18; TAF9B; LHX3; ERCC2; ZNF557; ZBED2; OSR2; GRIP1; PRDM12; NR0B1; ZIC4; RARG; SSX7; MLLT1; TRPS1; SOHLH2; SNAI1; IRF1; NFIC; YBX2; ELK4; ZBTB44; ZNF778; TFAP2A; ZNF74; ETV3; CBX4; PAX4; ZNF787; KLF15; BAZ2A; HOXD13; ZNF532; IKZF3; ZBTB7C; EVX1; TBR1; DBP; TEAD3; ACTL6B; TULP2; ERBB4; MAPK8IP1; ZNF157; TAF6; CREG1; NR1H3; ARNT2; NEUROD2; FOXF2; ZNF440; ZNF480; SOX1; MNX1; HES2; ZNF492; SP140L; ID3; ZIM2; BRWD1; PRRX1; HHEX; RSF1; ATF3; EMX2; WT1; PBX2; ZNF227; FOXA1; ZSCAN18; TBX21; KLF11; ARRB1; FOSB; ZNF423; ARID1A; ZNF239; ZNF33B; ZNF165; POU2F2; PRDM2; GTF2I; TBX1; ZNF34; MTA2; INSR; NEUROG1; TXNIP; ZNF329; PEG3; PGR; PRDM5; NFATC1; MXI1; ZNF93; FLI1; HIPK3; PITX1; NKX2-2; ID1; EPAS1; PPP1R13L; ZFP36L2; VPS72; ARID5A; POU3F2; PRMT2; TOX; TOPORS; MYCN; ZNF426; POU5F1B; HMGA1; CTNNB1; HIC2; FOXN3; LHX6; BPTF; EYA2; MYT1; KAT6B; BAZ2B; TFEB; ZNF552; ZBTB16; HOXB5; NR1H2; ZNF652; KLF3; LEF1; CNBP; NFE2L3; CRYM; TCEB2; ZFHX3; HOXB13; JAK2; EN1; HIRA; WWP1; TULP3; MEIS1; ARNTL2; MYRF; HLX; PLAGL1; SOX2; TRIM22; NFAT5; MNDA; NCOA3; TCF7; TGIF1; NR2F1; NR1D2; PAX5; TSC22D1; IRF9; HMBOX1; NFE2; INSM1; TFEC; SMAD6; SPIB; SOX11; RBBP8; PAX6; MEOX2; CEBPB; MKL2; NANOG; IKZF1; POU2AF1; GTF3A; TAL1; SMARCA1; MSX1; BHLHE41; DACH1; LITAF; HEY1; EGR2; THAP11; E2F2; GATA2
Down-regulation 183 CCNA2; FHL2; XBP1; HOXA5; NUP62; PUF60; CRK; ATF1; BRCA1; USP22; BASP1; PAX8; SUV39H1; EED; FOXO3; HNRNPD; NFIL3; HDAC2; TBP; EZH2; SNW1; RBM14; TCERG1; CDK7; ING2; NFKBIA; MED1; NCOA6; SOX4; CTCF; ADNP; ECD; SSRP1; SFPQ; HOXA10; HIF1A; HMGB2; FOSL1; HOXC6; CENPF; SF1; NPM1; SCAND1; KDM2A; MED6; CRY1; EDF1; PSMC3IP; BLM; SMARCA5; SUZ12; VEZF1; GTF2A2; ZNF146; SMAD3; NRIP1; REST; ZBTB11; TRIM32; AATF; BRD3; ZFP64; CCDC59; DNAJC2; RAN; TRIM16; UBE2I; HOXC10; TSC22D2; TBPL1; DDX54; RNF111; WHSC1; TAF5; FOXD1; TLE1; ZBTB24; MED27; ITGB3BP; SMARCE1; BAZ1B; KAT7; CBX3; SOX9; MLX; CTBP2; KLF6; PATZ1; DEK; PKNOX1; PPRC1; GATAD2A; ZNF189; BCLAF1; IRF7; YWHAB; BMI1; NFKB1; MTDH; AFF1; CHD7; ANKRD1; ZNF266; BAZ1A; JARID2; CTBP1; CTR9; RBBP4; NPAT; CREB3L1; MBD2; POLR2A; ATF4; RBL1; NCOA4; TAF1D; APEX1; ASXL1; PHF20; PCGF2; TCF20; FOXC1; ZBTB18; RBPJ; CCNE1; NCOR2; SMAD2; SMAD1; ZMYM2; MGA; TRIM29; ZNF410; MAX; NELFB; TP53; RBM39; HOXB7; NRBF2; MTF2; HOXA11; NR2F2; CDYL; NR2F6; ENO1; RNF138; FOXJ3; BATF3; DDX17; ING3; HSBP1; NKX3-1; ELF1; PTTG1; BIRC2; PQBP1; TBL1X; TLE4; CITED1; DNMT3B; ZIC1; HSF2; CBFB; ZNF302; HMGB1; COPS5; SIX1; DDX5; ZNF217; BTG1; REPIN1; MED13; GTF2IRD1; SAP30; BBX; MYB; FLNA; STAT3; ZBTB38; TRIP6; PBX3; MEOX1; SATB1; NR3C1