Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09657 Cgp-60474 GSE70138 HA1E Human 24h 3.33uM EID0003
Types Number Response transcription factors
Up-regulation 661 EGR1; CEBPD; MEF2C; SPDEF; ZNF235; CIITA; ZNF544; ZNF154; PRDM1; PRDM14; GBX1; ZNF274; RFX1; CBFA2T3; ZNF500; FOS; THRB; PROP1; THRA; HSF4; ZNF586; ZNF345; MED12; ZSCAN32; IRF6; NFE2L2; MYCL; ZNF117; CDX1; SCAI; SSBP3; ASH1L; HEYL; ZXDC; NFKB2; SRY; NKX3-2; ZNF688; SOX3; ZNF141; ZNF273; TCEA2; ZNF665; ZNF816; SIX6; ASCL3; ONECUT1; ZNF551; ZNF136; PAX1; TAF1C; MZF1; SALL2; CDIP1; TBL1Y; ZNF415; CD3D; ATN1; ZNF467; AR; RFX3; JUP; CBX4; KDM5C; HOXC5; NFATC4; ZNF264; ZNF180; SIX3; FOXH1; ZNF394; E4F1; ERBB4; FOXJ1; RING1; ZNF225; HOXD3; FEZF2; ZNF253; ALX4; KLF8; ZNF778; TP73; ZKSCAN8; ZNF667; BCL11A; HIF3A; MEIS2; ZNF606; E2F4; ZBTB3; ZNF835; LHX3; ZNF221; PAX6; TAF1; ALX3; NEUROD4; ZNF304; TRIB3; HNF1A; ZNF814; SPI1; SOX18; MAML3; CRTC1; POU6F2; RBPJL; ZNF550; ZNF701; ZIC3; NR6A1; TEF; SOX17; FOXP3; CHD2; ZNF215; HDAC11; ACTL6B; BARX1; INSR; ZNF44; CUX2; HOXB1; ZNF75D; ZNF132; ZNF91; ESRRB; ZNF254; ZNF155; ZBED2; ZNF682; ZNF549; ZNF671; HLX; RORB; TAF6L; LIN28A; ETV1; NR5A2; ZNF710; FOXJ2; CDX4; ZNF573; NR2E1; CARF; ATF6B; ZNF8; NKX2-5; ZNF770; MED25; HDAC5; ZNF224; ZNF471; ZSCAN2; PBXIP1; RAX; IRF3; ZNF529; ZNF343; PRDM9; NEUROD6; ZFHX2; ZBTB7B; NFIX; ZNF695; ATOH1; LDB1; HESX1; POU6F1; EMX1; HIC2; ZBTB44; POU4F3; SIX5; HDAC9; EZH1; ESR1; TONSL; ZNF331; MYNN; ETV2; ZNF350; SCRT1; AIRE; ZNF85; NEUROG2; ARL2BP; NR1I3; RORC; ZNF611; ZNF174; TSHZ2; CNOT3; MED31; ZNF362; DOT1L; ZNF208; TLX1; HNF4G; ZNF43; NEUROG3; POU2F3; EP300; ZNF391; CALCOCO1; PDX1; NEUROD2; CAMTA2; CRX; PRDM12; POU3F3; FOXE3; VENTX; ZNF124; MECP2; KLF15; BAZ2A; ZNF10; LBX1; LZTR1; SOX1; CBX2; WNT4; HOXB8; ARID3B; ZNF771; SSX7; ZSCAN9; REL; FOXF2; SRCAP; TBX5; NOCT; ZNF557; ETV3; ZKSCAN4; ZNF507; ATF7; FOXN1; SOX21; HIVEP3; ZBTB39; ZNF528; ZNF223; HINFP; TLX2; BRWD1; HBP1; ZNF76; HAND2; PAX3; MLLT1; HHEX; TULP2; PNRC1; ZNF93; TBX19; ZBTB48; FOXD3; SUPT7L; RFX2; CALR; VSX1; CBX7; NPAS1; ZNF675; L3MBTL1; ZNF423; ZNF749; GBX2; OVOL1; TULP1; ZNF257; PRDM2; IKZF2; EHMT2; AFF3; KDM4C; ZNF134; NFIC; ZNF214; ID4; ZNF780B; NR1H4; CEBPE; VHL; ZKSCAN3; HNF4A; TFDP3; GSC2; ZNF407; VGLL1; ZNF669; FOXB1; SUPT3H; MAP3K10; ZNF135; PBX1; SOX13; DCC; SHOX2; KLF11; ARID3A; SIN3B; PPARA; CBL; HIPK2; LMX1B; GTF2A1; TLX3; ZNF480; TCF4; ZNF35; MNX1; SOX14; ZNF195; ZNF329; ZNF81; OVOL2; ZXDB; ZNF430; KLF13; TEAD3; FOXI1; TBX6; TCF21; POU1F1; CBX8; MAPK8IP1; ZNF440; PAX7; ZFP2; SOX5; GRIP1; ING4; SNAPC4; ZSCAN31; GFI1B; HOXD12; HOXA3; ZNF442; AEBP1; HES2; GCM2; RARG; ZNF74; ZSCAN18; TWIST1; FOXL1; ZNF34; NHLH2; ZBTB43; IRF8; KMT2D; MDM4; FOXF1; NR2C2; SP4; ZFPM2; ZNF211; TFAP2A; ZNF83; RFXAP; MYRF; RORA; ZNF287; ZNF219; TUB; EYA3; ST18; PRRX1; MTA2; JAK2; TFAP4; ZIC4; HOXA2; TBR1; TBX4; ZNF674; ZNF571; MYEF2; ZNF205; NHLH1; ZNF222; ZNF142; KAT6A; NEUROD1; ZNF79; ZNF80; SHOX; NR5A1; UTF1; CREBL2; ZNF157; NR4A1; ZFP69B; ZNF613; NR0B1; ZNF426; PAX4; ZNF14; MDM2; IKZF3; GFI1; PRDM10; TAF4B; ZIM2; CSDC2; ZNF493; SMARCB1; PIAS4; WHSC1L1; SETDB1; PBX2; FHL5; ZNF484; ARNT2; MAK; THAP9; TFEC; FLI1; BRD4; ZNF324; NR4A2; HOXC8; SKIL; ZNF250; NACA2; NEUROG1; ZNF41; EN2; CITED2; TBX21; CEBPA; DLX6; BRDT; GATA6; OLIG2; MNDA; ZNF335; HOXD1; ZNF112; ZNF334; STAT4; ZNF107; ASCL2; CREG1; DMRT1; POU3F4; TBX1; MSX2; HEY2; GATA1; MAFK; ESR2; ZNF492; ZNF286A; PRDM13; THAP7; RSF1; KLF7; SOX30; HOXD13; WT1; OSR2; ZNF444; ZNF711; ZNF177; CIR1; WDR77; ESRRA; YAP1; ETV7; AFF2; ZFY; POU4F2; PHF1; HAND1; POU2F1; CRYM; DLX5; NKX6-1; ARRB1; MEF2D; KAT2B; ZNF787; MXD1; ZFP37; TAF5L; HIC1; VPS72; GCM1; BRF2; ZNF562; BNC1; MKL1; IRF1; SP1; INSM1; ARID5A; PRDM5; ZNF268; PRDM16; ONECUT2; ZNF232; DBP; SOX15; ZNF580; NFX1; LHX2; TAF1A; ZNF506; NR1H2; ZNF140; ARID1A; STAT2; EN1; TXNIP; MEOX2; HSF1; TRIM22; HOXD11; ZKSCAN7; SNAI1; CNOT2; NANOG; ZNF419; MYT1; EVX1; ERCC2; ETV5; ZBTB7C; TRPS1; TGFB1; NR2C1; CERS4; ZNF623; BNC2; ATF7IP; NR0B2; ZNF239; MYCN; HOXD9; EMX2; PRMT2; RBFOX2; GRHL2; HOXD10; MED17; ZNF552; EPAS1; PHF8; HIPK1; CTNNB1; KMT2A; NCOA3; SKI; MBD4; IRF9; HOXC4; TULP3; NKX2-2; SALL1; TCF7L2; BARX2; HOXB5; SP140L; FOXA2; ATF3; ZFHX3; PEG3; LHX6; DLX4; SOHLH2; PGR; NR4A3; CDK9; CERS6; POU3F2; NFATC1; ZNF532; BACH2; SP140; NAB2; ZKSCAN1; TTF2; NR2F1; PSMC3; ZNF175; MYT1L; ZNF654; JUN; KLF4; KLF9; RCOR3; HMBOX1; THAP10; ESRRG; FOXA1; FOSB; ISL1; EGR4; NPAS2; KLF1; SPIB; CREM; PITX1; PIAS1; ZNF589; WWP1; ZNF12; POU5F1B; TCEB2; NFE2L3; HOXB2; ZBTB20; MXI1; EYA1; ZFP36L2; FOXL2; EGR2; ARNTL2; CEBPG; LITAF; TGIF2; EHF; SOX2; GLI2; TAL1; TGIF1; NR1H3; HIRA; MKL2; BRD2; PLAGL1; TFDP2; NFE2; E2F5; YBX3; ASCL1; DLX2; MEOX1; ZMYND8; IRF4; SSX1; ZHX2; HEY1; SOX11; EGR3; MEIS1; MAF; BHLHE41; E2F2; ZEB1; FOXG1; IKZF1; MAFB; POU2AF1; GATA2; SSBP2
Down-regulation 180 FHL2; CCNA2; HOXA5; XBP1; HDAC2; ATF1; PUF60; NFKBIA; BASP1; NUP62; USP22; NFIL3; SUV39H1; GTF2A2; ECD; MYC; HNRNPD; NCOA4; FOXO3; TBP; SNW1; SCAND1; BHLHE40; FOSL1; ING2; LOXL2; EZH2; ATF6; BRCA1; CRK; PAX8; SETD2; SFPQ; HOXA10; RBM14; MAGED1; VEZF1; TP53; SMAD2; CTR9; RBBP4; HIF1A; EDF1; SMARCA5; SMAD3; SOX4; CRY1; RAN; NPM1; CENPF; CBX3; RB1; UBE2I; ZNF146; TSC22D2; MED1; MBD2; DNAJC2; ASXL1; HOXC6; BMI1; NRIP1; ZFP64; TCERG1; DEK; PATZ1; CDK7; SSRP1; NCOR2; BRD8; NELFB; PHF20; FOXJ3; ENO1; BLM; REPIN1; NCOA6; ZBTB11; PRPF6; ADNP; PSPC1; BCLAF1; CCDC59; ITGB3BP; NFKB1; AFF1; NRBF2; TBPL1; EED; BIRC2; HMGB2; ID2; RUNX1; MLX; SIX1; MED4; BRD3; BRPF1; REST; SMARCE1; YWHAB; ZBTB38; GTF2IRD1; KDM2A; DDX5; SAP30; RFC1; ELF1; NPAT; ATF4; TLE1; DDX17; RNF111; NONO; MED6; ZNF593; SMARCC1; TAF9; RNF4; NR2F2; PLAGL2; CBFB; LPIN2; TRIM16; PIAS2; ARID4B; MTDH; TRIM32; TRIM27; CEBPZ; DNAJC1; PPRC1; TGFB1I1; TFAM; CDYL; HOXB7; TCF12; ZBTB18; MEF2A; HSBP1; TSG101; ZNF189; MAX; PCGF2; RUVBL2; NFE2L1; STAT3; DNMT3B; BAZ1B; PTTG1; FOXM1; TAF10; KAT7; FOXC1; FOSL2; TMF1; COPS5; HOXC10; ZMYM2; CCNC; JARID2; ELK3; SERTAD2; ZNF302; APEX1; PURA; RNF6; FLNA; RNF138; TBL1X; GTF3A; ELF5; BBX; TSC22D1; MYBL1; PBX3; SMARCA2; NKX3-1; SATB1; NR3C1