Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09656 Cgp-60474 GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 737 CEBPD; MEF2C; GBX1; EGR1; SPDEF; ZNF154; PRDM14; ZNF264; PAX6; AR; FOXO4; SCAI; ZNF544; ZNF345; CBFA2T3; ZNF75D; RFX1; ZNF136; ZNF273; FOXJ1; ZNF500; PAX1; HIF3A; NFKBIB; HEYL; ASCL3; SIX6; BCL11A; HDAC5; PROP1; FOXH1; RFX3; NFATC4; THRB; MECP2; ZFHX2; CARF; ZNF611; ZNF235; SALL2; ZNF8; ZNF274; ZNF778; ZNF816; SRY; ALX4; FEZF2; ZNF665; HSF4; CBX4; SOX21; MAML3; ZNF573; TAF1C; ZNF10; ZNF91; ONECUT1; NEUROD2; ZNF701; LHX3; ZNF814; ETV1; ZBTB44; REL; ZNF117; ZNF695; ZNF180; ZNF550; ZNF43; ASH1L; RING1; NFE2L2; ZNF688; L3MBTL1; RBPJL; SPI1; TP73; CD3D; ZNF551; ESRRB; RORC; ZNF93; ZBTB48; ZNF221; MYCL; CIITA; ZNF141; HOXA3; POU6F2; ZNF667; NR5A1; ZNF343; ATN1; ALX3; ZNF254; NFKB2; NEUROD4; LZTR1; ZNF44; ZNF467; TCEA2; NR4A3; SSBP3; CRTC1; TBL1Y; LIN28A; CHD2; RFX2; HOXB1; ERBB4; ZSCAN32; CDX1; SCRT1; LDB1; PRDM9; NHLH1; E2F4; NR6A1; POU3F3; ATOH1; EP300; ZKSCAN8; ZNF606; ZNF549; ZNF682; TEF; KLF15; TLX3; HOXB8; ZNF471; ZBTB7B; IRF6; MED12; HDAC11; ZNF529; DOT1L; ZNF239; THRA; OVOL2; ZNF771; FOS; PDX1; ZNF224; GRIP1; HNF4G; ZNF391; ZNF85; IKZF4; AIRE; NOCT; CDX4; ZNF253; TFDP3; FOXE3; BARX1; ZNF287; HIPK2; EMX1; ZNF669; ZNF586; CBX2; KLF13; FOXD3; ST18; SOX17; ETV3; TULP1; ZNF225; VGLL1; HOXC5; CDIP1; ZKSCAN4; ZNF835; ZNF223; CRX; ING4; CSDC2; ACTL6B; BRWD1; AFF3; ZSCAN9; POU6F1; FOXB1; ZNF415; ZBED2; SNAPC4; POU4F3; ZSCAN2; TAF4B; ZNF331; MED31; ZBTB43; ATF7; ZNF362; TUB; ZNF571; NEUROD6; ZNF430; TBX5; ZNF350; GFI1B; TBX4; TSHZ2; RORB; NKX3-2; ZNF749; TCF21; ZNF135; LMX1B; SUPT3H; NFIX; TLX1; SIX3; NEUROG3; PAX7; MED25; PRDM2; HAND2; ZNF83; FOXP3; ESR2; ZIC3; SOX18; MZF1; TAF1; HINFP; SOX3; TBX19; MYF5; NEUROG2; MEIS2; SSX7; ZNF132; SP4; ZNF155; ZNF407; SOX5; VENTX; TFEC; HLX; ZNF142; ZNF174; GSC2; ZXDB; ETV2; MAP3K10; PBXIP1; ZNF214; POU2F1; TULP2; ZNF711; HNF4A; HNF1B; MAK; PRDM1; ZNF76; NEUROG1; ZNF787; ZKSCAN3; ZNF442; FOXN1; IRF1; HNF1A; MLLT1; ZNF257; KLF8; TLX2; FOXL1; ZNF80; ZNF440; ZNF507; RAX; OVOL1; HESX1; NR2E1; ZNF81; TCF4; ARHGAP35; JUP; CAMTA2; ZNF324; GCM2; NRL; PBX2; TONSL; HOXC8; ESR1; IKZF3; NR1I3; MYNN; E4F1; NPAS1; ZNF222; INSR; LBX1; SKI; ZNF780B; TAF6L; PNRC1; ZNF304; ZNF208; WNT4; ZSCAN31; ATF6B; CREG1; TBR1; ZNF157; VHL; CEBPE; VSX1; ZNF329; ZIM2; LHX5; TBX10; NFX1; EHMT2; ARL2BP; ZNF423; ZNF556; ZNF674; GATA1; NR0B2; HOXA2; PRDM8; EMX2; HOXD3; HOXD12; SOX14; ZBTB3; SOX1; PBX1; ZIC4; POU2F3; NHLH2; BRDT; ZNF770; PRDM12; ZNF394; IRF8; ZNF41; ZNF484; KMT2D; ZNF134; ZNF195; ZFP2; PPARA; POU1F1; ZNF671; THAP9; ZFPM2; PAX3; NEUROD1; DLX5; ZFY; NKX6-1; IKZF2; PRDM5; CEBPA; HOXA6; ZNF613; ONECUT2; SNAI1; EYA3; PITX3; TBX21; ZNF493; FOXF1; TFAP2A; GCM1; ZBTB17; CBX8; TBX6; WHSC1L1; CALR; ZNF234; SRCAP; ZNF408; NKX2-5; SIX5; MXD1; MEF2D; HHEX; HES2; ZNF250; NANOG; PAX4; EHF; ZNF324B; ZNF675; THAP3; KDM5C; ZNF768; PRRX1; ZNF74; INSM1; ZNF764; RSF1; SHOX; HMX1; MYRF; HBP1; HIC1; TRIB3; ZNF34; KDM4C; CBX7; ZNF215; ETV7; ARID3B; RBL2; MAPK8IP1; SETDB1; EVX1; KDM5A; TRIM24; ZNF124; VPS72; HOXB5; ZNF639; ZNF668; NR4A2; NR4A1; NKX2-8; ZNF426; STAT2; CUX2; ZNF480; ZNF536; GBX2; HIVEP3; MNX1; ZNF107; DBP; ZNF446; KAT2A; ZBTB6; ZBTB39; ASCL2; ZNF197; MNDA; PRDM16; SHOX2; ZXDC; ERCC2; NACA2; FOXA1; HMBOX1; SOX30; SOX13; AFF2; ZNF710; NFIC; ZBTB20; ZKSCAN7; SSX3; ZNF334; PPARD; CCNT1; PHIP; PHF1; ZNF219; ZNF492; ZNF614; E2F1; NKX2-2; MSX2; EZH1; SOHLH2; NR5A2; NR1H4; GTF2A1; DMRT1; HDAC9; ZNF506; FOXA2; ZNF696; CNOT2; POU3F4; DCC; ZNF232; CIR1; PRDM10; ZFP69B; SOX12; FOXN3; UTF1; MDM2; HIC2; GRHL2; WT1; ZNF528; PPP1R13L; HLF; RARG; ZNF175; ARID4A; NR2C2; PLAGL1; FOXI1; DLX6; ZFP37; MTA2; BRF2; ZNF557; RUNX2; POU4F2; ZNF184; SMARCD1; JAK2; FLI1; CREBL2; TEAD3; FOXC2; ZNF211; HSF1; NFATC1; BAZ2A; FOXN2; ZNF202; ZNF460; CNOT3; ZNF205; TFAP4; ELF2; ZBTB7C; FEV; NAB2; HAND1; PRDM13; ELK4; ARNT2; CRYM; KLF1; MYEF2; LMO1; GON4L; MYT1; ZNF562; ZNF79; FHL5; ARID5A; TXNIP; EPAS1; NR2C1; BAZ2B; CREB5; NR0B1; ZNF35; MDM4; YBX2; IRF3; TRAF6; ZIC1; ZNF652; CHD3; POU5F1B; PEG3; TCF7L2; TGIF1; ZNF574; OLIG2; ARID3A; EN1; MYT1L; CITED2; ZNF510; TWIST1; MXD3; TRPS1; CERS6; GFI1; NR1H3; ZNF587; BNC1; LHX6; NR1I2; TBX1; ZSCAN18; FOXF2; ARNT; FOXL2; SCMH1; ZNF623; MBD4; ZNF444; CAMTA1; CIC; PAX2; PKNOX2; ZNF3; CREM; HMGB3; DYRK1B; SIM1; POU2F2; POU3F2; GCFC2; DLX4; LHX2; CREBZF; BNC2; ZNF140; ZNF286A; TGFB1; PAXBP1; HOXD13; FOSB; ZNF177; MXI1; KLF7; SKIL; ZNF654; KLF9; TULP3; BCL6; SUPT5H; BARX2; PITX1; LYL1; ARID1A; NR1H2; KAT2B; ZNF227; ZNF112; JUND; ZNF14; TFDP2; ZFHX3; CDX2; ZNF419; ISL1; ZNF33B; ZNF165; GLI3; HOXD1; ZNF532; NFAT5; HOXB13; ZNF589; ZHX2; ZBTB16; TCF3; CREB3L2; ZNF160; PIAS3; SATB2; KLF3; LHX1; TGIF2; ZNF354A; PEX14; TGS1; SP140; MYOG; HOXB2; TOPORS; SLC2A4RG; SOX2; KLF11; ZNF552; SPIB; EBF2; PGR; NCOA3; IRX5; RBFOX2; STAT4; SMARCA1; EGR4; PHOX2A; HEY2; ZNF512B; ZNF580; JUN; ZNF148; HOXC4; MLXIPL; ZNF133; TAL1; AES; TCEA1; ZNF22; ZKSCAN1; LITAF; HDGF; BRD2; RXRG; GATA6; MYCN; NFE2; NKX2-1; AEBP1; BHLHE41; RORA; MEIS1; SALL1; ATF3; TFEB; SMARCC2; IRF9; SOX11; MAFF; BACH2; KAT6B; OSR2; TOX; FUBP1; ERG; ZNF721; ID4; E2F5; ASCL1; DLX2; KDM5D; GLI2; KLF4; TCEB2; NR1D2; NPAS2; TLE2; PAX5; IKZF1; MSX1; POU2AF1; BRD4; HIRA; MECOM; MYB; NR2F1; CREB1; AHR; SSBP2; MEOX2; THAP11; DACH1; E2F2; GATA2
Down-regulation 171 FHL2; CCNA2; XBP1; PUF60; HOXA5; NUP62; HDAC2; HNRNPD; ECD; ATF1; VGLL4; BRCA1; CRK; USP22; MAGED1; SCAND1; FOXO3; EZH2; NFKBIA; NFIL3; SUV39H1; MYC; UBE2I; GTF2A2; TFDP1; TBP; LOXL2; NCOA4; VEZF1; SFPQ; NR2F2; RBM14; RB1; ID2; SNW1; MED1; SMAD3; BHLHE40; SMARCC1; NRIP1; SOX4; FOXJ3; EED; DNAJC2; HOXC6; BRD8; EDF1; HOXA10; NCOA6; SMARCA5; RBBP4; MED6; CRY1; PCGF2; DRAP1; CENPF; BIRC2; RAN; FOSL1; ZNF672; TRIM32; TCF12; ATF4; BMI1; CBFB; RBBP7; NRBF2; RNF111; FLNA; RUNX1; NCOR2; TP53; BLM; SMAD2; NPM1; BRD3; TLE1; CNOT1; HDAC1; PHF20; MLX; KAT7; ZNF146; SETD2; ELK3; PREB; AATF; MBD2; CEBPZ; RNF6; REST; ARID4B; DR1; CTR9; NELFB; ELF1; MAX; CBX3; SMARCE1; MED4; TGFB1I1; CCNC; AFF1; PSMC3IP; CCDC59; CDK7; BCLAF1; ZBTB40; SAP30; KLF10; ITGB3BP; DEK; PQBP1; TRIP4; MED27; ING2; PRPF6; FOXC1; RNF4; TRIM27; PATZ1; MYBL1; NPAT; PAX8; XRCC6; JARID2; NFKB1; FOXD1; ENO1; SERTAD2; TAF10; MEF2A; ANKRD1; SF1; TAF9; TSC22D2; ELF5; IKBKAP; ZMIZ1; COPS5; TBL1X; GTF2IRD1; APEX1; TRIM28; ZMYM2; HMGN3; PTTG1; YWHAB; HOXC10; CITED1; RCOR1; TLE4; STAT3; DMTF1; STAT6; BAZ1A; MLXIP; RBBP8; HOXB7; CREB3L1; SIX2; DDX5; PIR; NKX3-1; SMAD1; LEF1; TRIM29; ZBTB18; NFATC3; NR3C1; SATB1