Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09653 Nvp-aew541 GSE70138 HA1E Human 24h 0.37uM EID0003
Types Number Response transcription factors
Up-regulation 97 CCNH; TRIB3; IKZF1; PRRX1; MED15; ARNT2; PHIP; HDAC5; PNRC1; ZNF273; NFIC; NCOA2; CNOT2; HBP1; POLR3C; CALCOCO1; GCFC2; EMX2; ATN1; SRCAP; FOXJ1; IRF6; PRDM12; FOXI1; PIAS1; SSBP3; STAT6; CBFA2T3; PRDM14; NR0B2; TULP3; INSR; ZNF227; NFATC4; NAB2; LDB1; HLF; ZNF12; MKL2; HDGF; CDIP1; KLF13; HIPK1; NR2E1; ATF3; ZNF117; ZNF195; PLAGL1; HIPK2; FOXF2; FOXM1; RAD21; KLF11; CNBP; SMAD1; VGLL1; ZFP36L2; ZNF573; NR1H4; PRDM2; ID4; LYL1; DLX5; ARID5B; ZNF232; TXNIP; CRYM; POU5F1B; OSR2; AEBP1; LHX6; HMBOX1; TRPS1; BCL11A; BRD4; CITED2; LITAF; RORA; TBX2; TWIST1; NEUROD1; NFIB; MITF; VDR; ZBTB16; CALR; MXI1; YBX3; HHEX; AHR; ST18; MECOM; MYBL1; TFAP2C; MEOX2; GATA2; SNAI2
Down-regulation 45 BASP1; EDF1; EZH2; CHD7; NKX3-1; TRIM16; NFKB1; RBM14; MAGED1; FOXD1; GATA4; HOXB7; TFAM; WHSC1; SIX1; PIAS2; SIM2; CITED1; NPM1; NCOR2; PRKDC; BCL3; SUB1; YWHAB; ZNF302; NAB1; WWC1; SIAH2; KLF2; BHLHE41; HOXC6; LMCD1; CERS6; PCGF2; DACH1; PTTG1; WT1; MAFB; BAZ1A; TRIM29; PEG3; SATB1; HES1; NR3C1; PPARG