Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09649 Pf-431396 GSE70138 HA1E Human 24h 0.04uM EID0003
Types Number Response transcription factors
Up-regulation 93 PAX6; SOHLH2; MED12; CBFA2T3; FOXN3; CAPN15; HIPK3; SSBP2; NFX1; TOX3; DNMT3B; HOXC11; RBBP7; SIM1; TLE4; SSX1; KLF6; SOX10; STAT2; ENO1; PHIP; RAD21; ZBTB43; EN1; TXNIP; NR1I2; ELF5; KLF9; RUNX3; ZNF611; EHF; BACH1; OVOL1; SERTAD2; CDK8; ZNF83; NHLH2; REL; SP110; SP100; TULP4; DACH1; HOXC10; BHLHE40; TSC22D3; LMCD1; PLAGL1; LHX6; SMARCE1; PITX2; NR4A1; NR4A3; MYCL; ZEB2; IRF7; KLF5; ZNF160; MLXIP; RAN; CUX1; INSM1; PURA; ZNF468; MYB; TFEB; CERS6; JUNB; ZNF721; YWHAB; PDLIM1; TOB1; SNAI2; STAT3; ZNF652; SP140L; KLF4; TP63; ETS2; PPARG; GATA6; HOXD1; KDM5D; FOSB; ASCL1; RBPMS; FOXC1; NR4A2; ZIC1; ZEB1; TOX; HOXC6; GATA2; SATB1
Down-regulation 45 CUX2; ETV5; ZBED2; HDAC4; AFF1; MLX; TCF25; THAP1; ZNF410; ZNF593; TGFB1I1; COPS2; CREBL2; IRX4; RUVBL2; RNF111; HOXD10; YBX3; HHEX; PCGF2; TEAD4; SMARCD3; ZNF217; MYRF; RBBP8; ARID1A; RBPJ; ZFP36L1; WWC1; BNC2; TWIST1; NKX3-1; ELK3; MNDA; BRD2; CITED1; POU2AF1; NANOG; MAFB; ZFP36L2; THAP11; MXI1; TFAP2C; PEG3; TBX2