Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09648 Pf-431396 GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 59 VGLL4; MNAT1; RUNX3; IKZF1; KLF6; DAXX; IRF6; NCOA3; LMCD1; DNAJC1; SMARCA5; ZNF165; TRIM29; KLF9; FOXN3; HSBP1; PPP1R13L; TULP4; CREM; FOXA1; OSR2; HOXA1; MYBL1; ELF5; RUNX1; PAX6; TFEC; KLF4; CREB3L1; SOX10; TXNIP; GRHL2; KLF5; INSR; EN1; FOSB; DNMT3B; NKX2-2; INSM1; PURA; ZNF264; TCF7L1; HOXC10; NR1D2; ZNF721; IRX5; TFAP2C; ETS2; TFEB; HTATIP2; SAP30; STAT4; PHF20; AEBP1; TBX3; SNAI2; HOXC6; SATB1; ABL1
Down-regulation 62 TAF5; ETV5; POLR3F; NR2F2; TCF7L2; PLAGL2; NRIP1; CALR; ZNF593; PHOX2A; ZBTB18; SMAD6; MAZ; ATF2; TAF4; THAP10; MDM2; FOXD1; DDIT3; ESRRG; CITED1; NFIC; HDAC9; EGR3; CSDE1; ARID1A; SOX9; ISL1; MYCN; BHLHE41; ID3; HAND1; HOXB13; KLF10; LEF1; SP3; SATB2; SUB1; NKX2-1; MXI1; STAT6; MKL2; CITED2; ID4; GTF3A; NFIB; FLNA; NR2F1; TOX; JUNB; ZNF423; MAFB; CREB1; ZFP36L1; MECOM; FOXG1; MEIS2; KDM5D; GATA2; NR3C1; TBX2; PPARG