Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09647 Pf-431396 GSE70138 HA1E Human 24h 0.37uM EID0003
Types Number Response transcription factors
Up-regulation 35 BRD8; KMT2A; TRIM32; SOX4; TULP3; RNF111; NCOA6; PEX2; TP63; KMT2B; HOXD1; DNMT3B; ATF7IP; TCF7; CHD9; EYA1; CUX1; SOX10; ZNF721; ARID1A; ZNF423; LITAF; MECOM; INSR; ID4; TFDP2; NPAS2; MEOX2; FOXC1; TRIM29; FOSB; TXNIP; SOX17; SATB1; ABL1
Down-regulation 60 ZNF593; TCF3; OVOL2; ZBTB11; TEAD1; CCDC59; HMGB2; HOXC6; PAXBP1; HIPK3; GTF2I; ERG; FOXL2; ZNF91; TSC22D2; TCF21; TFAM; IRF1; SIX1; ADNP2; NFATC3; CTBP1; AR; GATA4; RUVBL2; RCOR1; BCL11B; FOXO1; HOXB6; TOX3; NR1H3; MYCL; KLF11; BMI1; TAF10; APEX1; ZNF281; WT1; HOXB2; RNF138; RXRA; EGR3; NKX2-2; ASCL1; TFEC; FOSL2; MAF; PBX1; CEBPB; SOX9; MYB; TBX3; SOX11; PEG3; BHLHE41; TWIST1; ADRB2; GATA2; PPARG; TBX2