Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09646 Pf-431396 GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 82 TCFL5; VGLL4; JUNB; RUNX3; TERF2; HDAC4; PNRC1; HIVEP1; MNDA; SIRT2; RXRA; HMGA2; TOX3; ZNF184; TCF7; PIR; TSC22D4; NR4A2; JUP; TOB1; DPF2; ZEB2; CBX5; ETS2; HOXB7; TCF15; TCF20; SATB2; RNF111; CBX7; CERS6; HBP1; VDR; MAGED1; BTG1; TCF7L2; TP63; NPAS2; NPAT; NCOR2; KAT2B; IRF1; PRKDC; ZNF267; ADRB2; CBX6; TBL1XR1; BCL3; TFEB; ZNF217; REPIN1; NR3C2; IRF8; MYRF; TGIF1; ERG; ZNF536; ZKSCAN1; LEF1; PPARG; ZNF160; HLTF; PCGF2; MAFB; IRF9; SHOX2; ZHX2; HTATIP2; CITED2; FLNA; NFE2L3; FOSB; MYB; BHLHE41; ZFP36L1; ZEB1; ZNF331; ZNF423; EGR3; POU2AF1; SATB1; ABL1
Down-regulation 74 NPM1; CCNE1; CCNA2; LZTS1; RUVBL1; CBFB; C1QBP; HSBP1; VAX2; NFYA; ZNF281; BRDT; NR2E1; EGR4; YBX1; KLF7; NFIB; MSX1; CNBP; DNAJC2; CITED1; TAF10; ID4; WWC1; GTF3A; ENO1; CENPF; VGLL1; ZNF354A; RAN; HIPK3; ISL1; ZNF22; FUBP1; GRHL2; GTF2I; PHOX2B; GFI1; SIX3; JUND; PDLIM1; DLX2; ELF5; HMBOX1; FOXG1; MYBL1; CARHSP1; PRRX1; EYA2; PTTG1; HEY1; HMGN3; RBPJ; DLX5; PAX6; SMARCA1; EPAS1; NEUROD1; TCF7L1; HMGB1; IRX5; MEOX2; ZBTB38; MEOX1; RBPMS; ZIC1; MEIS1; MECOM; SOX11; TOX; MEIS2; ID1; TBX2; GATA2